Literature DB >> 9949947

Two novel biallelic polymorphisms in the IL-2 gene.

S John1, D Turner, R Donn, P Sinnott, J Worthington, W E Ollier, I V Hutchinson, A H Hajeer.   

Abstract

We have detected two novel single nucleotide polymorphisms in the IL-2 gene, at positions -330 and +166 relative to the transcription start site. The +166 change occurs within the leader peptide and does not affect amino acid sequence. The -330 polymorphism has two common alleles, making it an ideal marker for genetic association studies.

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Year:  1998        PMID: 9949947     DOI: 10.1046/j.1365-2370.1998.00139.x

Source DB:  PubMed          Journal:  Eur J Immunogenet        ISSN: 0960-7420


  13 in total

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Journal:  DNA Cell Biol       Date:  2012-04-03       Impact factor: 3.311

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Review 6.  Th1/Th2 cytokines and their genotypes as predictors of hepatitis B virus related hepatocellular carcinoma.

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7.  Correlation of -475 IL-2 Promoter Gene Polymorphisms and the Levels of Serum IL-2 on the Risk of Multiple Sclerosis.

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Journal:  Rep Biochem Mol Biol       Date:  2022-04

8.  Association study of interleukin 2 (IL2) and IL4 with schizophrenia in a Japanese population.

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9.  T helper 1 type cytokines polymorphisms: association with susceptibility to Behçet's disease.

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10.  The association of -330 interleukin-2 gene polymorphism with its plasma concentration in Iranian multiple sclerosis patients.

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Journal:  Scientifica (Cairo)       Date:  2014-05-19
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