Literature DB >> 994460

Golgi complex alterations induced by X537A in chief cells of rat parathyroid gland.

M Ravazzola.   

Abstract

Electron microscopic examination of chief cells of rat parathyroid glands incubated with the antibiotic ionophore X537A showed selective alterations of the Golgi complex. The changes were dependent on the duration of X537A exposure. After 50 minutes of incubation, the cisternae and vesicles of the Golgi complex appeared highly swollen and disorganized. Because of its selective action, X537A might be a useful tool in the investigation of the role of Golgi apparatus in parathormone secretion.

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Year:  1976        PMID： 994460

Source DB:  PubMed          Journal:  Lab Invest        ISSN： 0023-6837            Impact factor:   5.662


  5 in total

1.  Disruption of the Golgi zone and inhibition of the conversion of proparathyroid hormone to parathyroid hormone in human parathyroid tissue by tris(hydroxymethyl)aminomethane.

Authors:  D H McGregor; L L Chu; R R MacGregor; D V Cohn
Journal:  Am J Pathol       Date:  1977-06       Impact factor: 4.307

2.  The effects of tris(hydroxymethyl)aminomethane and calcium ionophores on the biosynthesis of proparathormone and the formation and degradation of parathormone in bovine parathyroid tissue.

Authors:  D H McGregor; J J Morrissey; D V Cohn
Journal:  Am J Pathol       Date:  1981-03       Impact factor: 4.307

3.  Plasma cell immunoglobulin secretion: arrest is accompanied by alterations of the golgi complex.

Authors:  A M Tartakoff; P Vassalli
Journal:  J Exp Med       Date:  1977-11-01       Impact factor: 14.307

4.  Immunocytochemical localization of procollagen and fibronectin in human fibroblasts: effects of the monovalent ionophore, monensin.

Authors:  P W Ledger; N Uchida; M L Tanzer
Journal:  J Cell Biol       Date:  1980-12       Impact factor: 10.539

5.  Stimulation of catecholamine secretion from cultured chromaffin cells by an ionophore-mediated rise in intracellular sodium.

Authors:  S J Suchard; F A Lattanzio; R W Rubin; B C Pressman
Journal:  J Cell Biol       Date:  1982-09       Impact factor: 10.539
  5 in total

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