Literature DB >> 993580

Mouse factor B of the alternative pathway of complement activation. I. Purification, characterization, and functional behavior.

D Bitter-Suermann, R Burger, V Brade, U Hadding.   

Abstract

Mouse factor B was purified and a monospecific antiserum was raised. The physicochemical data of this protein (108,000 m.w., 5.9 S, 5.9 to 6.05 isoelectric point) were determined. The functional behavior resembles that of human and guinea pig factor B and it operates efficiently in the C3 feedback cycle of the alternative pathway of complement activation. A provisional scheme is given for the operation of the C3bB enzyme on the cellular (macrophage) level.

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Year:  1976        PMID: 993580

Source DB:  PubMed          Journal:  J Immunol        ISSN: 0022-1767            Impact factor:   5.422


  10 in total

1.  Evidence for intrathecal synthesis of alternative pathway complement activation proteins in experimental meningitis.

Authors:  P F Stahel; K Frei; A Fontana; H P Eugster; B H Ault; S R Barnum
Journal:  Am J Pathol       Date:  1997-10       Impact factor: 4.307

2.  Regulation of macrophage migration by products of the complement system.

Authors:  C Bianco; O Götze; Z A Cohn
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

3.  Plasma membrane polypeptides of resident and activated mouse peritoneal macrophages.

Authors:  H L Yin; S Aley; C Bianco; Z A Cohn
Journal:  Proc Natl Acad Sci U S A       Date:  1980-04       Impact factor: 11.205

4.  Insoluble polyanions as activators of both pathways of complement.

Authors:  R Burger; D Bitter-Suermann; M Loos; U Hadding
Journal:  Immunology       Date:  1977-12       Impact factor: 7.397

5.  Solid phase activation of alternative pathway of complement by beta-1,3-glucans and its possible role for tumour regressing activity.

Authors:  J Hamuro; U Hadding; D Bitter-Suermann
Journal:  Immunology       Date:  1978-04       Impact factor: 7.397

6.  Isolation and characterization of rat complement factor B and its interaction with cell-bound human C3.

Authors:  M R Daha; L A van Es
Journal:  Immunology       Date:  1980-12       Impact factor: 7.397

7.  Murine complement factor B (BF): sexual dimorphism and H-2-linked polymorphism.

Authors:  M H Roos; P Démant
Journal:  Immunogenetics       Date:  1982-01       Impact factor: 2.846

8.  Studies on the possible involvement of complement component C3 in the initiation of acid hydrolase secretion by macrophages. I. Correlation between enzyme-releasing and complement-activating capacities of several secretagogues.

Authors:  D W Riches; D R Stanworth
Journal:  Immunology       Date:  1981-09       Impact factor: 7.397

9.  Structural polymorphism of murine factor B controlled by a locus closely linked to the H-2 complex and demonstration of multiple alleles.

Authors:  S Natsuume-Sakai; K Moriwaki; S Migita; K Sudo; K Suzuki; D Y Lu; C Wang; M Takahashi
Journal:  Immunogenetics       Date:  1983       Impact factor: 2.846

10.  Intense tumour-cell destruction by syngeneic mice: role of macrophages, complement activation and tumour-cell factors.

Authors:  S Orbach-Arbouys; J Lheritier; M Allouche; P Pouillart
Journal:  Br J Cancer       Date:  1977-12       Impact factor: 7.640

  10 in total

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