Literature DB >> 9935223

New DNA polymorphisms of human MMH/OGG1 gene: prevalence of one polymorphism among lung-adenocarcinoma patients in Japanese.

T Ishida1, R Takashima, M Fukayama, C Hamada, Y Hippo, T Fujii, S Moriyama, C Matsuba, Y Nakahori, H Morita, Y Yazaki, T Kodama, S Nishimura, H Aburatani.   

Abstract

MMH/OGG1 is an 8-hydroxyguanine-specific DNA glycosylase/AP-lyase, one of the mutator enzymes for the excision repair of 8-hydroxyguanine. DNA polymorphisms in human MMH/OGG1 gene were newly identified and analyzed to examine a possible association with lung-cancer risk by a population-based study. Polymorphic allele 3 in hMMH/OGG1 exon 1 was significantly prevalent among Japanese patients with adenocarcinoma of the lung [odds ratio (OR): 3.152, 95% confidence interval (CI): 1.266-7.845], indicating that the excision repair of 8-hydroxyguanine may play a role in predisposition to lung cancer.

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Year:  1999        PMID： 9935223     DOI： 10.1002/(sici)1097-0215(19990105)80:1<18::aid-ijc4>3.0.co;2-e

Source DB:  PubMed          Journal:  Int J Cancer        ISSN： 0020-7136            Impact factor:   7.396


  7 in total

1.  hOGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis.

Authors:  Peiliang Geng; Jie Yao; Yunfeng Zhu
Journal:  Mol Biol Rep       Date:  2014-01-17       Impact factor: 2.316

2.  Effect of single mutations in the OGG1 gene found in human tumors on the substrate specificity of the Ogg1 protein.

Authors:  M Audebert; J P Radicella; M Dizdaroglu
Journal:  Nucleic Acids Res       Date:  2000-07-15       Impact factor: 16.971

3.  The hOGG1 gene 5'-UTR variant c.-53G>C contributes to the risk of gastric cancer but not colorectal cancer in the Chinese population: the functional variation of hOGG1 for gastric cancer risk.

Authors:  Xiufang Liu; Nong Xiao; Wenwen Guo; Yijia Wu; Zhenming Cai; Qiong He; Lin Zhang; Xiaoxiang Chen; Caixia Sun; Jingmei Wang; Changdong Zhu; Heiying Jin; Yaping Wang
Journal:  J Cancer Res Clin Oncol       Date:  2011-08-06       Impact factor: 4.553

4.  Polymorphisms of DNA repair genes XRCC1 and XRCC3, interaction with environmental exposure and risk of chronic gastritis and gastric cancer.

Authors:  Márcia Cristina Duarte; Jucimara Colombo; Andrea Regina Baptista Rossit; Alaor Caetano; Aldenis Albaneze Borim; Durval Wornrath; Ana Elizabete Silva
Journal:  World J Gastroenterol       Date:  2005-11-14       Impact factor: 5.742

Review 5.  8-Hydroxyguanine: From its discovery in 1983 to the present status.

Authors:  Susumu Nishimura
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2006-05       Impact factor: 3.493

6.  Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer.

Authors:  Kazuya Shinmura; Masanori Goto; Hong Tao; Hisami Kato; Rie Suzuki; Satoki Nakamura; Tomonari Matsuda; Guang Yin; Makiko Morita; Suminori Kono; Haruhiko Sugimura
Journal:  Oxid Med Cell Longev       Date:  2014-03-23       Impact factor: 6.543

7.  [Mutational analysis of hOGG1 gene promoter in patients with non-small cell lung cancer].

Authors:  Xia Liu; Jun Zhao; Rengyun Liu; Zhe Lei; Jiacong You; Qinghua Zhou; Hong-Tao Zhang
Journal:  Zhongguo Fei Ai Za Zhi       Date:  2011-03
  7 in total

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