Literature DB >> 9934491

Novel cytokine release inhibitors. Part III: Truncated analogs of tripterine.

W He1, F C Huang, A Gavai, W K Chan, G Amato, K T Yu, A Zilberstein.   

Abstract

Truncated analogs of tripterine as cytokine (IL-1 alpha, IL-1 beta, TNF-alpha, IL-6, and IL-8) release inhibitors are discussed.

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Year:  1998        PMID： 9934491     DOI： 10.1016/s0960-894x(98)00671-4

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  9 in total

Review 1.  Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae).

Authors:  Anita M Brinker; Jun Ma; Peter E Lipsky; Ilya Raskin
Journal:  Phytochemistry       Date:  2007-01-23       Impact factor: 4.072

2.  Celastrol analogues as inducers of the heat shock response. Design and synthesis of affinity probes for the identification of protein targets.

Authors:  Lada Klaić; Richard I Morimoto; Richard B Silverman
Journal:  ACS Chem Biol       Date:  2012-03-14       Impact factor: 5.100

3.  Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor.

Authors:  Vivek R Yadav; Bokyung Sung; Sahdeo Prasad; Ramaswamy Kannappan; Sung-Gook Cho; Mingyao Liu; Madan M Chaturvedi; Bharat B Aggarwal
Journal:  J Mol Med (Berl)       Date:  2010-08-27       Impact factor: 4.599

4.  Pristimerin Inhibits LPS-Triggered Neurotoxicity in BV-2 Microglia Cells Through Modulating IRAK1/TRAF6/TAK1-Mediated NF-κB and AP-1 Signaling Pathways In Vitro.

Authors:  Bin Hui; Liping Zhang; Qinhua Zhou; Ling Hui
Journal:  Neurotox Res       Date:  2017-11-08       Impact factor: 3.911

5.  Tripterine prevents endothelial barrier dysfunction by inhibiting endogenous peroxynitrite formation.

Authors:  Feng Wu; Min Han; John X Wilson
Journal:  Br J Pharmacol       Date:  2009-06-05       Impact factor: 8.739

6.  Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule.

Authors:  Amy Trott; James D West; Lada Klaić; Sandy D Westerheide; Richard B Silverman; Richard I Morimoto; Kevin A Morano
Journal:  Mol Biol Cell       Date:  2008-01-16       Impact factor: 4.138

7.  Novel Low-Toxic Derivative of Celastrol Maintains Protective Effect against Acute Renal Injury.

Authors:  Xun Hu; Mengdi Jia; Yu Fu; Pei Zhang; Zhirong Zhang; Qing Lin
Journal:  ACS Omega       Date:  2018-03-06

8.  Celastrol inhibits gastric cancer growth by induction of apoptosis and autophagy.

Authors:  Hyun-Woo Lee; Kenny Seung Bin Jang; Hye Ji Choi; Ara Jo; Jae-Ho Cheong; Kyung-Hee Chun
Journal:  BMB Rep       Date:  2014-12       Impact factor: 4.778

9.  Celastrol inhibits colorectal cancer through TGF-β1/Smad signaling.

Authors:  Zhitao Jiang; Qianyu Cao; Guoliang Dai; Jianchun Wang; Chundi Liu; Lingyan Lv; Jinhuo Pan
Journal:  Onco Targets Ther       Date:  2019-01-09       Impact factor: 4.147
  9 in total

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