Literature DB >> 9934471

Identification of novel nucleotide phosphonate analogs with potent anti-HCMV activity.

P Nguyen-Ba1, N Turcotte, L Yuen, J Bédard, M Quimpère, L Chan.   

Abstract

We have recently described the discovery of new leads in the area of anti-HCMV research. Further structure-activity relationship studies have allowed us to identify potent and selective anti-HCMV nucleotide analogs. The synthesis as well as structure-activity relationship studies are described.

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Year:  1998        PMID: 9934471     DOI: 10.1016/s0960-894x(98)00649-0

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  Synthesis of Methylenecyclopropane Analogues of Antiviral Nucleoside Phosphonates.

Authors:  Zhaohua Yan; Shaoman Zhou; Earl R Kern; Jiri Zemlicka
Journal:  Tetrahedron       Date:  2006-03-13       Impact factor: 2.457

2.  Novel isoxazolidine analogues of homonucleosides and homonucleotides.

Authors:  Dorota G Piotrowska; Jan Balzarini; Graciela Andrei; Dominique Schols; Robert Snoeck; Andrzej E Wróblewski; Joanna Gotkowska
Journal:  Tetrahedron       Date:  2016-11-02       Impact factor: 2.457

  2 in total

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