Literature DB >> 9933301

Linkage of a commoner form of recessive amyotrophic lateral sclerosis to chromosome 15q15-q22 markers.

A Hentati1, K Ouahchi, M A Pericak-Vance, D Nijhawan, A Ahmad, Y Yang, J Rimmler, W Hung, B Schlotter, A Ahmed, M Ben Hamida, F Hentati, T Siddique.   

Abstract

Autosomal recessive familial amyotrophic lateral sclerosis (RFALS) is a rare form of ALS that usually presents at an early age with slow progression of symptoms. RFALS is clinically and genetically heterogeneous and the locus of RFALS type 3 was mapped to 2q33 (ALS2) in a single family. We now report linkage of a more-common form of RFALS to chromosome 15q15-q22 markers (ALS5) and show further genetic locus heterogeneity in RFALS. ALS5 is the locus for most families with RFALS and appears to be present in both North African and European populations.

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Year:  1998        PMID： 9933301     DOI： 10.1007/s100480050052

Source DB:  PubMed          Journal:  Neurogenetics        ISSN： 1364-6745            Impact factor:   2.660


  33 in total

1.  A novel locus for familial amyotrophic lateral sclerosis, on chromosome 18q.

Authors:  Collette K Hand; Jawad Khoris; François Salachas; François Gros-Louis; Ana Amélia Simões Lopes; Veronique Mayeux-Portas; Carl G Brewer; Robert H Brown; Vincent Meininger; William Camu; Guy A Rouleau
Journal:  Am J Hum Genet       Date:  2001-11-09       Impact factor: 11.025

Review 2.  Progress in the pathogenesis of amyotrophic lateral sclerosis.

Authors:  C E Shaw; A al-Chalabi; N Leigh
Journal:  Curr Neurol Neurosci Rep       Date:  2001-01       Impact factor: 5.081

3.  Two families with familial amyotrophic lateral sclerosis are linked to a novel locus on chromosome 16q.

Authors:  Deborah M Ruddy; Matthew J Parton; Ammar Al-Chalabi; Cathryn M Lewis; Caroline Vance; Bradley N Smith; P Nigel Leigh; John F Powell; Teepu Siddique; Eelco Postumus Meyjes; Frank Baas; Vianney de Jong; Christopher E Shaw
Journal:  Am J Hum Genet       Date:  2003-07-01       Impact factor: 11.025

Review 4.  Complex genetics of amyotrophic lateral sclerosis.

Authors:  Catherine B Kunst
Journal:  Am J Hum Genet       Date:  2004-10-11       Impact factor: 11.025

Review 5.  Diagnostic investigation and multidisciplinary management in motor neuron disease.

Authors:  J A Rocha; C Reis; F Simões; J Fonseca; J Mendes Ribeiro
Journal:  J Neurol       Date:  2005-12       Impact factor: 4.849

6.  The evolving biology of cell reprogramming.

Authors:  Ian Wilmut; Gareth Sullivan; Ian Chambers
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2011-08-12       Impact factor: 6.237

7.  A new familial amyotrophic lateral sclerosis locus on chromosome 16q12.1-16q12.2.

Authors:  Halah Abalkhail; John Mitchell; James Habgood; Richard Orrell; Jacqueline de Belleroche
Journal:  Am J Hum Genet       Date:  2003-06-26       Impact factor: 11.025

8.  SPATACSIN mutations cause autosomal recessive juvenile amyotrophic lateral sclerosis.

Authors:  Antonio Orlacchio; Carla Babalini; Antonella Borreca; Clarice Patrono; Roberto Massa; Sarenur Basaran; Renato P Munhoz; Ekaterina A Rogaeva; Peter H St George-Hyslop; Giorgio Bernardi; Toshitaka Kawarai
Journal:  Brain       Date:  2010-01-28       Impact factor: 13.501

9.  Infantile-onset ascending hereditary spastic paralysis is associated with mutations in the alsin gene.

Authors:  Eleonore Eymard-Pierre; Gaetan Lesca; Sandra Dollet; Filippo Maria Santorelli; Matteo di Capua; Enrico Bertini; Odile Boespflug-Tanguy
Journal:  Am J Hum Genet       Date:  2002-07-26       Impact factor: 11.025

Review 10.  Amyotrophic lateral sclerosis.

Authors:  Lokesh C Wijesekera; P Nigel Leigh
Journal:  Orphanet J Rare Dis       Date:  2009-02-03       Impact factor: 4.123
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