Literature DB >> 9930400

Involvement of phospholipids in apolipoprotein B modification during low density lipoprotein oxidation.

A I Karakatsani1, T A Liapikos, A N Troganis, D C Tsoukatos.   

Abstract

An increased amount of phospholipids remained attached on delipidated apolipoprotein B originated from oxidized low density lipoprotein (LDL). 31P nuclear magnetic resonance analysis of such apolipoprotein showed an organic phosphorus peak at -0.55 ppm, which suggests the formation of adducts (most probably Schiff bases) of oxidized phospholipids with apolipoprotein B. The above reaction occurs in parallel with the hydrolysis of oxidized phospholipids, catalyzed by the LDL-attached platelet-activating factor acetylhydrolase, and may contribute to the proatherogenic effect of oxidatively modified low density lipoprotein.

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Year:  1998        PMID： 9930400     DOI： 10.1007/s11745-998-0318-3

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  24 in total

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Authors:  H Esterbauer; J Gebicki; H Puhl; G Jürgens
Journal:  Free Radic Biol Med       Date:  1992-10       Impact factor: 7.376

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Journal:  N Engl J Med       Date:  1989-04-06       Impact factor: 91.245

5.  Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediated catabolism.

Authors:  U P Steinbrecher; J L Witztum; S Parthasarathy; D Steinberg
Journal:  Arteriosclerosis       Date:  1987 Mar-Apr

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Journal:  Proc Natl Acad Sci U S A       Date:  1979-01       Impact factor: 11.205

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Authors:  U P Steinbrecher
Journal:  J Biol Chem       Date:  1987-03-15       Impact factor: 5.157

8.  Recognition of solubilized apoproteins from delipidated, oxidized low density lipoprotein (LDL) by the acetyl-LDL receptor.

Authors:  S Parthasarathy; L G Fong; D Otero; D Steinberg
Journal:  Proc Natl Acad Sci U S A       Date:  1987-01       Impact factor: 11.205

9.  An oxidized derivative of phosphatidylcholine is a substrate for the platelet-activating factor acetylhydrolase from human plasma.

Authors:  K E Stremler; D M Stafforini; S M Prescott; G A Zimmerman; T M McIntyre
Journal:  J Biol Chem       Date:  1989-04-05       Impact factor: 5.157

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Journal:  Atherosclerosis       Date:  1976 Jul-Aug       Impact factor: 5.162
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  5 in total

1.  Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: evidence that oxidation-specific epitopes mediate macrophage recognition.

Authors:  M K Chang; C Bergmark; A Laurila; S Hörkkö; K H Han; P Friedman; E A Dennis; J L Witztum
Journal:  Proc Natl Acad Sci U S A       Date:  1999-05-25       Impact factor: 11.205

2.  Platelet-activating factor acetylhydrolase and transacetylase activities in human plasma low-density lipoprotein.

Authors:  D C Tsoukatos; T A Liapikos; A D Tselepis; M J Chapman; E Ninio
Journal:  Biochem J       Date:  2001-07-15       Impact factor: 3.857

3.  Receptors for oxidized low-density lipoprotein on elicited mouse peritoneal macrophages can recognize both the modified lipid moieties and the modified protein moieties: implications with respect to macrophage recognition of apoptotic cells.

Authors:  D A Bird; K L Gillotte; S Hörkkö; P Friedman; E A Dennis; J L Witztum; D Steinberg
Journal:  Proc Natl Acad Sci U S A       Date:  1999-05-25       Impact factor: 11.205

4.  Polyunsaturated phospholipids promote the oxidation and fragmentation of gamma-hydroxyalkenals: formation and reactions of oxidatively truncated ether phospholipids.

Authors:  Xi Chen; Wujuan Zhang; James Laird; Stanley L Hazen; Robert G Salomon
Journal:  J Lipid Res       Date:  2007-12-29       Impact factor: 5.922

Review 5.  Lipoproteins as targets and markers of lipoxidation.

Authors:  Catarina B Afonso; Corinne M Spickett
Journal:  Redox Biol       Date:  2018-12-06       Impact factor: 11.799
  5 in total

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