Literature DB >> 9928732

Risk behavior and HIV infection among new drug injectors in the era of AIDS in New York City.

D C Des Jarlais1, S R Friedman, T Perlis, T F Chapman, J L Sotheran, D Paone, E Monterroso, A Neaigus.   

Abstract

OBJECTIVE: To examine HIV risk behavior and HIV infection among new initiates into illicit drug injection in New York City. DESIGN AND METHODS: Cross-sectional surveys of injecting drug users (IDUs) recruited from a large detoxification treatment program (n=2489) and a street store-front research site (n=2630) in New York City from 1990 through 1996. Interviews covering demographics, drug use history, and HIV risk behavior were administered; serum samples were collected for HIV testing. Subjects were categorized into two groups of newer injectors: very recent initiates (just began injecting through 3 years) and recent initiates (injecting 4-6 years); and long-term injectors (injecting > or = 7 years).
RESULTS: 954 of 5119 (19%) of the study subjects were newer injectors, essentially all of whom had begun injecting after knowledge about AIDS was widespread among IDUs in the city. New injectors were more likely to be female and white than long-term injectors, and new injectors were more likely to have begun injecting at an older age (median age at first injection for very recent initiates, 27 years; median age at first injection for recent initiates, 25 years; compared with median age at first injection for long-term injectors, 17 years). The newer injectors generally matched the long-term injectors in frequencies of HIV risk behavior; no significant differences were found among these groups on four measures of injection risk behavior. HIV infection was substantial among the newer injectors: HIV prevalence was 11% among the very recent initiates and 18% among the recent initiates. Among the new injectors, African Americans, Hispanics, females, and men who engaged in male-male sex were more likely to be infected.
CONCLUSIONS: The new injectors appear to have adopted the reduced risk injection practices of long-term injectors in the city. HIV infection among new injectors, however, must still be considered a considerable public health problem in New York City.

Entities:  

Mesh:

Year:  1999        PMID: 9928732     DOI: 10.1097/00042560-199901010-00010

Source DB:  PubMed          Journal:  J Acquir Immune Defic Syndr Hum Retrovirol        ISSN: 1077-9450


  39 in total

1.  HIV incidence among injection drug users in New York City, 1992-1997: evidence for a declining epidemic.

Authors:  D C Des Jarlais; M Marmor; P Friedmann; S Titus; E Aviles; S Deren; L Torian; D Glebatis; C Murrill; E Monterroso; S R Friedman
Journal:  Am J Public Health       Date:  2000-03       Impact factor: 9.308

2.  Factors associated with adolescent initiation of injection drug use.

Authors:  C M Fuller; D Vlahov; A M Arria; D C Ompad; R Garfein; S A Strathdee
Journal:  Public Health Rep       Date:  2001       Impact factor: 2.792

3.  Changes in HIV seroprevalence and related behaviors among male injection drug users who do and do not have sex with men: New York City, 1990-1999.

Authors:  Carey B Maslow; Samuel R Friedman; Theresa E Perlis; Russell Rockwell; Don C Des Jarlais
Journal:  Am J Public Health       Date:  2002-03       Impact factor: 9.308

4.  The Changing Epidemic of HIV.

Authors: 
Journal:  Curr Infect Dis Rep       Date:  2000-10       Impact factor: 3.725

5.  First injection of ketamine among young injection drug users (IDUs) in three U.S. cities.

Authors:  Stephen E Lankenau; Bill Sanders; Jennifer Jackson Bloom; Dodi Hathazi; Erica Alarcon; Stephanie Tortu; Michael C Clatts
Journal:  Drug Alcohol Depend       Date:  2006-09-18       Impact factor: 4.492

6.  Changes in HIV and AIDS in the United States: Entering the Third Decade.

Authors:  Scott Kellerman; Elin Begley; Brian Boyett; Hollie Clark; Jeff Schulden
Journal:  Curr Infect Dis Rep       Date:  2005-03       Impact factor: 3.725

7.  Effects of race, neighborhood, and social network on age at initiation of injection drug use.

Authors:  Crystal M Fuller; Luisa N Borrell; Carl A Latkin; Sandro Galea; Danielle C Ompad; Steffanie A Strathdee; David Vlahov
Journal:  Am J Public Health       Date:  2005-04       Impact factor: 9.308

8.  Influence of Injection Drug Use-Related HIV Acquisition on CD4 Response to First Antiretroviral Therapy Regimen Among Virally Suppressed Individuals.

Authors:  Keri L Calkins; Catherine R Lesko; Geetanjali Chander; Richard D Moore; Bryan Lau
Journal:  J Acquir Immune Defic Syndr       Date:  2018-03-01       Impact factor: 3.731

9.  Socio-demographic factors, health risks and harms associated with early initiation of injection among people who inject drugs in Tallinn, Estonia: evidence from cross-sectional surveys.

Authors:  Sigrid Vorobjov; Don C Des Jarlais; Katri Abel-Ollo; Ave Talu; Kristi Rüütel; Anneli Uusküla
Journal:  Int J Drug Policy       Date:  2012-10-01

10.  Gender differences in circumstances surrounding first injection experience of rural injection drug users in the United States.

Authors:  April M Young; Nika Larian; Jennifer R Havens
Journal:  Drug Alcohol Depend       Date:  2013-10-27       Impact factor: 4.492

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