| Literature DB >> 9925541 |
C Petit1, V Yardley, F Gaboriau, J Bolard, S L Croft.
Abstract
The heat treatment of amphotericin B deoxycholate (Fungizone), which was previously shown to induce superaggregation and decrease the toxicity of the drug to mammalian cells, increased its activity against Leishmania donovani in BALB/c mice, whereas it reduced its toxicity. Heat treatment preserved the activity of Fungizone against L. donovani HU3-infected mouse peritoneal macrophages.Entities:
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Year: 1999 PMID: 9925541 PMCID: PMC89086
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191