| Literature DB >> 9925440 |
L Yang1, G Morriello, K Prendergast, K Cheng, T Jacks, W W Chan, K D Schleim, R G Smith, A A Patchett.
Abstract
Systematic SAR studies of the different regioisomers and homologues of the spiro(indane-1,4-piperidine) moiety in the growth hormone secretagogue L-162,752 are presented. Among them, spiro(3H-1-benzopyran-2,3-piperidine) was found to afford secretagogues with low nanomolar in vitro activity.Entities:
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Year: 1998 PMID： 9925440 DOI： 10.1016/s0960-894x(97)10199-8
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823