Literature DB >> 992505

A method of preparation and application of nitrous acid as a mutagen in Claviceps purpurea.

K Strnadová.   

Abstract

A simple and speedy procedure is described for the preparation and application of nitrous acid in mutagenic experiments. The conventional incubation mixture of sodium nitrite solution with acetate buffer is replaced by an aqueous solution of nitrous acid prepared by running a solution of sodium nitrite through a column of ion exchange. The procedure eliminates also the interference of other substances. Experimental appraisal of the technique was done during the mutagenic improval of the fungus Claviceps purpurea.

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Year:  1976        PMID: 992505     DOI: 10.1007/bf02876936

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN: 0015-5632            Impact factor:   2.099


  8 in total

1.  EFFECTS OF NITROUS ACID ON THE DAT COPOLYMER AS A TEMPLATE FOR DNA POLYMERASE.

Authors:  T KOTAKA; R L BALDWIN
Journal:  J Mol Biol       Date:  1964-08       Impact factor: 5.469

2.  IDENTIFICATION OF THE ALTERED BASES IN MUTATED SINGLE-STRANDED DNA. I. IN VITRO MUTAGENESIS BY HYDROXYLAMINE, ETHYL METHANESULFONATE AND NITROUS ACID.

Authors:  I TESSMAN; R K PODDAR; S KUMAR
Journal:  J Mol Biol       Date:  1964-08       Impact factor: 5.469

3.  [The inactivating and mutagenic effect of nitrous acid on cells of Escherichia coli].

Authors:  F KAUDEWITZ
Journal:  Z Naturforsch B       Date:  1959 Aug-Sep       Impact factor: 1.047

4.  Distribution of x-ray- and nitrous acid-induced mutations in the genetic fine structure of the ad7 locus of Schizosaccharomyces pombe.

Authors:  H GUTZ
Journal:  Nature       Date:  1961-09-09       Impact factor: 49.962

5.  [Production of mutations in tobacco mosaic virus by chemical treatment of its nucleic acid in vitro].

Authors:  K W MUNDRY; A GIERER
Journal:  Z Vererbungsl       Date:  1958

6.  [Method of chemical determination of the biologically active unit of ribonucleic acid in tobacco mosaic virus].

Authors:  H SCHUSTER; G SCHRAMM
Journal:  Z Naturforsch B       Date:  1958-11       Impact factor: 1.047

7.  Production of bacterial mutants with nitrous acid.

Authors:  F KAUDEWITZ
Journal:  Nature       Date:  1959-06-27       Impact factor: 49.962

8.  Identification of the altered bases in mutated single-stranded DNA. IV. Nitrous acid induction of the transitions guanine to adenine and thymine to cytosine.

Authors:  A S Vanderbilt; I Tessman
Journal:  Genetics       Date:  1970-09       Impact factor: 4.562

  8 in total

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