F Drago1, A Rebora. 1. Department of Dermatology, University of Genoa, Italy.
Abstract
OBJECTIVES: To discuss the current knowledge of 3 recently discovered human herpesviruses (HHV-6, HHV-7, and HHV-8), and to provide a dermatological point of view. DATA SOURCES: References identified from bibliographies of pertinent articles in the English language. STUDY SELECTION AND DATA EXTRACTION: Articles were selected according to their impact factor and the interest for dermatologists. DATA SYNTHESIS: As the other members of the family Herpesviridae, HHV-6, HHV-7, and HHV-8 may cause a primary infection, establish latent infection in a specific set of cells of their host, and then reactivate if conditions of altered immunity develop. The main pathological conditions associated with them are discussed. CONCLUSIONS: Human herpesvirus 6, HHV-7, and HHV-8 have provided new insights in some dermatological diseases. Although new studies are needed, they may have a profound impact on dermatology in the years to come.
OBJECTIVES: To discuss the current knowledge of 3 recently discovered human herpesviruses (HHV-6, HHV-7, and HHV-8), and to provide a dermatological point of view. DATA SOURCES: References identified from bibliographies of pertinent articles in the English language. STUDY SELECTION AND DATA EXTRACTION: Articles were selected according to their impact factor and the interest for dermatologists. DATA SYNTHESIS: As the other members of the family Herpesviridae, HHV-6, HHV-7, and HHV-8 may cause a primary infection, establish latent infection in a specific set of cells of their host, and then reactivate if conditions of altered immunity develop. The main pathological conditions associated with them are discussed. CONCLUSIONS:Human herpesvirus 6, HHV-7, and HHV-8 have provided new insights in some dermatological diseases. Although new studies are needed, they may have a profound impact on dermatology in the years to come.