Literature DB >> 992279

A reproducible animal model of acute bleeding ulcer-the "ulcer maker".

R L Protell, F E Silverstein, J Piercey, M Dennis, W Sprake, C E Rubin.   

Abstract

An instrument has been developed which creates an experimental model of an acute bleeding gastric ulcer. The diameter and depth of these gastric ulcers are reproducible. The instrument can be used endoscopically or at laparotomy. Using this ulcer model nonsurgical modalities for the treatment of upper gastrointestinal bleeding can be compared in a controlled manner. This standard experimental model may also facilitate comparison of results among different research groups.

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Year:  1976        PMID： 992279

Source DB:  PubMed          Journal:  Gastroenterology        ISSN： 0016-5085            Impact factor:   22.682


  16 in total

1.  A randomised controlled comparison of injection, thermal, and mechanical endoscopic methods of haemostasis on mesenteric vessels.

Authors:  C C Hepworth; S S Kadirkamanathan; F Gong; C P Swain
Journal:  Gut       Date:  1998-04       Impact factor: 23.059

2.  Evaluation of electrofulguration in control of bleeding of experimental gastric ulcers.

Authors:  M B Dennis; J Peoples; R Hulett; D C Auth; R L Protell; C E Rubin; F E Silverstein
Journal:  Dig Dis Sci       Date:  1979-11       Impact factor: 3.199

3.  NdYAG laser photocoagulation in the dog stomach.

Authors:  S G Bown; P R Salmon; D W Storey; B M Calder; D F Kelly; N Adams; H Pearson; B M Weaver
Journal:  Gut       Date:  1980-10       Impact factor: 23.059

4.  Endoscopic treatment of gastrointestinal bleeding. Topical therapy and variceal injection.

Authors:  S E Silvis
Journal:  Dig Dis Sci       Date:  1981-07       Impact factor: 3.199

5.  Nature and extent of histological changes induced by argon laser photocoagulation in canine gastric mucosa.

Authors:  D F Kelly; S G Bown; P R Salmon; B M Calder; H Pearson; B M Weaver
Journal:  Gut       Date:  1980-12       Impact factor: 23.059

6.  Safety and efficacy of Neodymium-Yag laser photocoagulation: an experimental study in dogs.

Authors:  P Rutgeerts; G Vantrappen; K Geboes; L Broeckaert
Journal:  Gut       Date:  1981-01       Impact factor: 23.059

7.  Creation of an effective and reproducible nonsurvival porcine model that simulates actively bleeding peptic ulcers.

Authors:  Victor K Chen; Jeffrey M Marks; Richard C K Wong; Michael F McGee; Ashley L Faulx; Gerard A Isenberg; Steven J Schomisc; Cheri X Deng; Jeffrey L Ponsky; Amitabh Chak
Journal:  Gastrointest Endosc       Date:  2008-07-11       Impact factor: 9.427

8.  Endoscopic bipolar electrocoagulation: development of a new bipolar coagulator for stopping gastrointestinal bleeding.

Authors:  H Yamamoto; K Hajiro; H Matsui; D Tsujimura; T Yamamoto
Journal:  Gastroenterol Jpn       Date:  1982-04

9.  Argon laser photocoagulation in the dog stomach.

Authors:  S G Bown; P R Salmon; D F Kelly; B M Calder; H Pearson; B M Weaver; A E Read
Journal:  Gut       Date:  1979-08       Impact factor: 23.059

10.  Failure of cyanoacrylate tissue glue (Flucrylate, MBR4197) to stop bleeding from experimental canine gastric ulcers.

Authors:  R L Protell; F E Silverstein; C Gulacsik; T R Martin; M B Dennis; D C Auth; C E Rubin
Journal:  Am J Dig Dis       Date:  1978-10
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