Literature DB >> 9921361

Splenic palpation for the evaluation of morbidity due to schistosomiasis mansoni.

R Gerspacher-Lara1, R A Pinto-Silva, J C Serufo, A A Rayes, S C Drummond, J R Lambertucci.   

Abstract

This study was undertaken to determine the accuracy of splenic palpation for the diagnosis of splenomegaly, and to determine whether the frequency of individuals with a palpable spleen in an endemic area can be considered as an index of morbidity of schistosomiasis. For the clinical diagnosis of splenomegaly, two criteria have been tested: (A) presence of a palpable spleen and (B) presence of a palpable spleen whose border could be felt more than 4 cm below the costal margin. In an area of high prevalence of the disease (66.3%) 285 individuals aged 18 years or more have been submitted to abdominal ultrasonography and physical examination. Splenomegaly was defined as a splenic length greater than 120 mm by ultrasound and the sensitivity, specificity, positive and negative predictive values of criterion A were 72.2%, 90.5%, 35.1% and 97.8%. The values for criterion B were 27.8%, 98%, 50% and 95%, respectively. In an non endemic area, 517 individuals were submitted to the same protocol and 22 individuals had a palpable spleen, but no patient fulfilled criterion B for splenomegaly, and only one met the ultrasonographic criterion for splenomegaly. The authors concluded that abdominal palpation is a poor method for the diagnosis of splenomegaly.

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Year:  1998        PMID: 9921361     DOI: 10.1590/s0074-02761998000700045

Source DB:  PubMed          Journal:  Mem Inst Oswaldo Cruz        ISSN: 0074-0276            Impact factor:   2.743


  2 in total

1.  Biosensor for Hepatocellular Injury Corresponds to Experimental Scoring of Hepatosplenic Schistosomiasis in Mice.

Authors:  Martina Sombetzki; Nicole Koslowski; Sandra Doss; Micha Loebermann; Michael Trauner; Emil C Reisinger; Martin Sauer
Journal:  Biomed Res Int       Date:  2016-06-08       Impact factor: 3.411

2.  Schistosoma mansoni-Associated Morbidity among Preschool-Aged Children along the Shores of Lake Victoria in Uganda.

Authors:  Allen Nalugwa; Fred Nuwaha; Edridah Muheki Tukahebwa; Annette Olsen
Journal:  Trop Med Infect Dis       Date:  2017-11-05
  2 in total

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