Genital manifestations of schistosomiasis mansoni in women: important but neglected.

Egg-induced lesions in the upper and the lower female reproductive tract are important complications of the infection with Schistosoma mansoni. The understanding of the pathophysiology and pathology of genital lesions is only rudimentary, simple and reliable diagnostic tools are not at hand, epidemiological data do not exist and how to treat best the women affected, is not known. In view of recent advances in the understanding of genital lesions induced by S. haematobium the existing literature is critically analyzed and possible consequences of female genital schistosomiasis are outlined. We estimate that 6 to 27% girls and women with intestinal schistosomiasis, at least temporarily, suffer from pathology induced by eggs sequestered somewhere in their genital organs. This is a matter of concern and warrants more research into the epidemiology, pathology, diagnosis and therapy of this disease entity.