| Literature DB >> 9920779 |
T Ishikawa1, T Igarashi, K Hata, T Fujita.
Abstract
c-fos mRNA is induced by many types of noxious stimuli that are known to enhance transcription mediated by the heat shock element (HSE). Nonetheless, it has been accepted that the c-fos promoter does not contain an HSE. In this report, we revealed that the human and rodent c-fos promoters do contain HSEs which are highly responsive to heat, arsenite, and cadmium. These HSEs may play important roles in regulating c-fos expression in various pathological and physiological situations. Copyright 1999 Academic Press.Entities:
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Year: 1999 PMID: 9920779 DOI: 10.1006/bbrc.1998.9979
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN: 0006-291X Impact factor: 3.575