Literature DB >> 992001

The origin of experimental brain tumours: a sequential study.

P L Lantos, D J Cox.   

Abstract

A sequential study of rat brains treated transplacetally with the neurotropic carcinogen ethylnitrosourea reveals small foci of cell proliferations from the age of 8 weeks. These lesions consist mainly of undifferentiated cells of the subependymal plate type. They occur in those areas in which gliomas develop and represent the earliest, histologically detectable, changes in the development of brain tumours.

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Year:  1976        PMID: 992001     DOI: 10.1007/bf01937439

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  9 in total

1.  Sequential development of ethylnitrosourea-induced neurinomas: morphology, biochemistry, and transplantability.

Authors:  J A Swenberg; N Clendenon; R Denlinger; W A Gordon
Journal:  J Natl Cancer Inst       Date:  1975-07       Impact factor: 13.506

Review 2.  Chemical carcinogenesis in the nervous system.

Authors:  P Kleihues; P L Lantos; P N Magee
Journal:  Int Rev Exp Pathol       Date:  1976

3.  Transplacental production with ethylnitrosourea of neoplasms of the nervous system in Sprague-Dawley rats.

Authors:  A Koestner; J A Swenberg; W Wechsler
Journal:  Am J Pathol       Date:  1971-04       Impact factor: 4.307

4.  [Organotropic carcinogenic effects of 65 various N-nitroso- compounds on BD rats].

Authors:  H Druckrey; R Preussmann; S Ivankovic; D Schmähl
Journal:  Z Krebsforsch       Date:  1967

5.  [Transplacental induction of malignant tumors of the nervous system. I. Ethyl-nitroso-urea (ENU) in BD IX rats].

Authors:  S Ivankovic; H Druckrey
Journal:  Z Krebsforsch       Date:  1968

6.  Tumours of the nervous system induced in rats by the neonatal administration of N-ethyl-N-nitrosourea.

Authors:  E L Jones; C E Searle; W T Smith
Journal:  J Pathol       Date:  1973-02       Impact factor: 7.996

7.  The ultrastructure of the subependymal plate in the rat.

Authors:  W F Blakemore
Journal:  J Anat       Date:  1969-05       Impact factor: 2.610

Review 8.  Toxicity of nitrosamines: their possible human health hazards.

Authors:  P N Magee
Journal:  Food Cosmet Toxicol       Date:  1971-04

9.  Teratogenic and carcinogenic effects in the offspring after single injection of ethylnitrosourea to pregnant rats.

Authors:  H Druckrey; S Ivanković; R Preussmann
Journal:  Nature       Date:  1966-06-25       Impact factor: 49.962

  9 in total
  22 in total

1.  The role of the subependymal plate in the origin of gliomas induced by ethylnitrosourea in the rat brain.

Authors:  P L Lantos
Journal:  Experientia       Date:  1977-04-15

2.  A Prospective Cohort Study of Neural Progenitor Cell-Sparing Radiation Therapy Plus Temozolomide for Newly Diagnosed Patients With Glioblastoma.

Authors:  Chengcheng Gui; Tracy D Vannorsdall; Lawrence R Kleinberg; Ryan Assadi; Joseph A Moore; Chen Hu; Alfredo Quiñones-Hinojosa; Kristin J Redmond
Journal:  Neurosurgery       Date:  2020-07-01       Impact factor: 4.654

3.  Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea.

Authors:  Taichang Jang; Todd Savarese; Hoi Pang Low; Sunchin Kim; Hannes Vogel; David Lapointe; Timothy Duong; N Scott Litofsky; James M Weimann; Alonzo H Ross; Lawrence Recht
Journal:  Am J Pathol       Date:  2006-05       Impact factor: 4.307

Review 4.  Invasiveness of primary brain tumors.

Authors:  O D Laerum; R Bjerkvig; S K Steinsvåg; L de Ridder
Journal:  Cancer Metastasis Rev       Date:  1984       Impact factor: 9.264

5.  Rhinencephalic glial cell nests and their possible role in glioma formation: morphometric studies do not reveal significant differences between brachycephalic and dolichocephalic dogs.

Authors:  G Obermaier; A Reihlen; E Dahme; S Weis
Journal:  Acta Neuropathol       Date:  1995       Impact factor: 17.088

6.  Relationship between glial reaction to a stab wound and tumor development after receiving transplacental ethylnitrosourea in the rat.

Authors:  D Schiffer; M T Giordana; M C Vigliani; P Cavalla
Journal:  Acta Neuropathol       Date:  1991       Impact factor: 17.088

7.  The development of experimental brain tumours. A sequential light and electron microscope study of the subependymal plate. I. Early lesions (abnormal cell clusters).

Authors:  P L Lantos; G J Pilkington
Journal:  Acta Neuropathol       Date:  1979-03-15       Impact factor: 17.088

8.  The development of experimental brain tumours a sequential light and electron microscope study of the subependymal plate. II. Microtumours.

Authors:  G J Pilkington; P L Lantos
Journal:  Acta Neuropathol       Date:  1979-03-15       Impact factor: 17.088

9.  Effect of dietary vitamin A or N-acetylcysteine on ethylnitrosourea-induced rat gliomas.

Authors:  D A Ross; P Kish; K M Muraszko; M Blaivas; M Strawderman
Journal:  J Neurooncol       Date:  1998-10       Impact factor: 4.130

10.  Experimental brain tumors by transplacental ENU. Multifactorial study of the latency period.

Authors:  D Schiffer; M T Giordana; A Mauro; G Racagni; F Bruno; S Pezzotta; P Paoletti
Journal:  Acta Neuropathol       Date:  1980       Impact factor: 17.088

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