Literature DB >> 9919720

Effects of gamma-radiation on ovarian follicles.

Y K Lee1, H H Chang, W R Kim, J K Kim, Y D Yoon.   

Abstract

In order to observe the morphological and endocrinological changes of the rat and mouse ovarian follicles by gamma-radiation, rats were whole-body irradiated with doses of 3.2 Gy and 8.0 Gy and mice with 2.9 Gy and 7.2 Gy. Sections of ovaria were examined by light microscopy. Concentrations of progesterone, testosterone, and estradiol in ovarian homogenate were determined by radioimmunoassay techniques. Gamma-radiation resulted in the increased percentage of atretic follicles in the groups killed on day 0, day 4, and day 8 after irradiation. The decrease in granulosa cell viability was found in animals killed on day 4 after irradiation. The finding of the high ratio of testosterone to estradiol compared to that of progesterone to testosterone suggests that aromatase activity--steroid biosynthesis from testosterone to estradiol--in granulosa cell could be affected by gamma-radiation.

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Year:  1998        PMID： 9919720

Source DB:  PubMed          Journal:  Arh Hig Rada Toksikol        ISSN： 0004-1254            Impact factor:   1.948


  7 in total

1.  Increased Radioresistance to Lethal Doses of Gamma Rays in Mice and Rats after Exposure to Microwave Radiation Emitted by a GSM Mobile Phone Simulator.

Authors:  Smj Mortazavi; Ma Mosleh-Shirazi; Ar Tavassoli; M Taheri; Ar Mehdizadeh; Sas Namazi; A Jamali; R Ghalandari; S Bonyadi; M Haghani; M Shafie
Journal:  Dose Response       Date:  2012-07-02       Impact factor: 2.658

2.  Associations of ionizing radiation and breast cancer-related serum hormone and growth factor levels in cancer-free female A-bomb survivors.

Authors:  Eric J Grant; Kazuo Neriishi; John Cologne; Hidetaka Eguchi; Tomonori Hayashi; Susan Geyer; Shizue Izumi; Nobuo Nishi; Charles Land; Richard G Stevens; Gerald B Sharp; Kei Nakachi
Journal:  Radiat Res       Date:  2011-06-30       Impact factor: 2.841

3.  Sodium selenite improves folliculogenesis in radiation-induced ovarian failure: a mechanistic approach.

Authors:  Riham S Said; Ahmed S Nada; Ebtehal El-Demerdash
Journal:  PLoS One       Date:  2012-12-06       Impact factor: 3.240

4.  Growth Hormone Ameliorates the Radiotherapy-Induced Ovarian Follicular Loss in Rats: Impact on Oxidative Stress, Apoptosis and IGF-1/IGF-1R Axis.

Authors:  Yasmen F Mahran; Ebtehal El-Demerdash; Ahmed S Nada; Reem N El-Naga; Azza A Ali; Ashraf B Abdel-Naim
Journal:  PLoS One       Date:  2015-10-14       Impact factor: 3.240

5.  Applying Broadband Dielectric Spectroscopy (BDS) for the Biophysical Characterization of Mammalian Tissues under a Variety of Cellular Stresses.

Authors:  Maria P Souli; Panagiotis Klonos; Adamantia F Fragopoulou; Ifigeneia V Mavragani; Ioannis S Pateras; Nikolaos Kostomitsopoulos; Lukas H Margaritis; Pavlos Zoumpoulis; Loukas Kaklamanis; Dimitris Kletsas; Vassilis G Gorgoulis; Apostolos Kyritsis; Polycarpos Pissis; Alexandros G Georgakilas
Journal:  Int J Mol Sci       Date:  2017-04-15       Impact factor: 5.923

6.  Examination of the effect of ovarian radiation injury induced by hysterosalpingography on ovarian proliferating cell nuclear antigen and the radioprotective effect of amifostine: an experimental study.

Authors:  Behzat Can; Remzi Atilgan; Sehmus Pala; Tuncay Kuloğlu; Sule Kiray; Nevin Ilhan
Journal:  Drug Des Devel Ther       Date:  2018-05-25       Impact factor: 4.162

7.  Phytoestrogen genistein hinders ovarian oxidative damage and apoptotic cell death-induced by ionizing radiation: co-operative role of ER-β, TGF-β, and FOXL-2.

Authors:  Yasmin Hamdy Haddad; Riham S Said; Rehab Kamel; Engy M El Morsy; Ebtehal El-Demerdash
Journal:  Sci Rep       Date:  2020-08-11       Impact factor: 4.379
  7 in total

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