Literature DB >> 991451

Serum inhibitory factors (SIF) in patients with acute and chronic hepatitis and their clinical significance.

N Brattig, P A Berg.   

Abstract

Serum inhibitory factors (SIF) were demonstrated in a follow-up study in eighteen patients with HBSAg-positive viral hepatitis, in nine patients with chronic persistent hepatitis (CPH) and in six patients with progressive viral hepatitis (CAH). In addition these factors were studied in fifteen patients with HBSAg-positive and HBSAg-negative CAH. SIF appeared during the incubation period up to 4 weeks before onset and disappeared in most instances within 4 weeks after onset of jaundice. Sera from patients with CPH showed no marked inhibitory activity when studied over a period of up to 3 years as compared to patients with a progressive course of hepatitis. The presense of SIF may depend upon persistence of virus, and may help to predict the development of chronic hepatitis.

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Year:  1976        PMID: 991451      PMCID: PMC1541369     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN: 0009-9104            Impact factor:   4.330


  22 in total

1.  Inhibitory effect of sera from patients with Botkin's viral hepatitis on the differentiation and mitotic activity of lymphocytes and integrity of their chromosomes in the course of serial passaging in vitro.

Authors:  O V Baroyan; I F Barinsky; A A Shatkin
Journal:  Acta Virol       Date:  1970-07       Impact factor: 1.162

2.  The effect of measles virus infection on T and B lymphocytes in the mouse. I. Suppression of helper cell activity.

Authors:  H F McFarland
Journal:  J Immunol       Date:  1974-12       Impact factor: 5.422

3.  Viral inhibition of the phytohemagglutinin response of human lymphocytes and application to viral hepatitis.

Authors:  F T Willems; J L Melnick; W E Rawls
Journal:  Proc Soc Exp Biol Med       Date:  1969-02

4.  Reduced lymphocyte transformation due to a plasma factor in patients with active syphilis.

Authors:  G M Levene; J L Turk; D J Wright; A G Grimble
Journal:  Lancet       Date:  1969-08-02       Impact factor: 79.321

5.  A rapid micro-method for the phytohaemagglutinin-induced human lymphocyte transformation test.

Authors:  W J Penhale; A Farmer; A C Maccuish; W J Irvine
Journal:  Clin Exp Immunol       Date:  1974-09       Impact factor: 4.330

6.  Immunological studies in patients with chronic active hepatitis. Cytotoxic activity of lymphocytes to autochthonous liver cells grown in tissue culture.

Authors:  F Paronetto; S Vernace
Journal:  Clin Exp Immunol       Date:  1975-01       Impact factor: 4.330

7.  Immune reactions in acute viral hepatitis.

Authors:  D I Newble; K T Holmes; A G Wangel; I J Forbes
Journal:  Clin Exp Immunol       Date:  1975-04       Impact factor: 4.330

8.  Cell-mediated immunity in acute and chronic hepatitis.

Authors:  J R Wands; J L Perrotto; E Alpert; K J Isselbacher
Journal:  J Clin Invest       Date:  1975-05       Impact factor: 14.808

9.  Lymphocyte transformation in leukemic serum.

Authors:  G B Humphrey; L Peterson; M Whalen; D E Parker; J Lankford; W Krivit; M Nesbit
Journal:  Cancer       Date:  1975-05       Impact factor: 6.860

10.  Lymphocyte E rosette inhibitory factor: a regulatory serum lipoprotein.

Authors:  F V Chisari; T S Edgington
Journal:  J Exp Med       Date:  1975-11-01       Impact factor: 14.307

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  7 in total

1.  Clinical significance of immunopathological findings in patients with post-pericardiotomy syndrome. II. The significance of serum inhibition and rosette inhibitory factors.

Authors:  B Maisch; P Schuff-Werner; P A Berg; K Kochsiek
Journal:  Clin Exp Immunol       Date:  1979-11       Impact factor: 4.330

2.  Delayed homograft rejection following common bile duct ligation: in vivo evidence that obstructive jaundice is immunosuppressive.

Authors:  R M Keane; P B Collins; A H Johnson; D Bouchier Hayes
Journal:  Ir J Med Sci       Date:  1986-05       Impact factor: 1.568

3.  [Immunsuppressive factors in sera and synovial fluids of patients with rheumatoid arthritis (author's transl)].

Authors:  A Lohrmann; P A Berg; S Goethe; G König
Journal:  Klin Wochenschr       Date:  1979-11-15

Review 4.  Autoantibodies and serum inhibition factors (sif) in patients with myocarditis.

Authors:  B Maisch; P A Berg; K Kochsiek
Journal:  Klin Wochenschr       Date:  1980-03-03

Review 5.  The immunopathology of acute type B hepatitis.

Authors:  L Bianchi
Journal:  Springer Semin Immunopathol       Date:  1981-04

6.  Suppressive effect of alcoholic liver disease sera on lymphocyte transformation.

Authors:  G P Young; F J Dudley; M B Van Der Weyden
Journal:  Gut       Date:  1979-10       Impact factor: 23.059

7.  Mitogen responsiveness in viral hepatitis and chronic active hepatitis: the role of reversible suppressive influences.

Authors:  C Feighery; J F Greally; D G Weir
Journal:  Gut       Date:  1980-09       Impact factor: 23.059

  7 in total

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