Literature DB >> 9914260

Tubulin structure: insights into microtubule properties and functions.

K H Downing1, E Nogales.   

Abstract

The structure of tubulin has recently been determined by electron crystallography, paving the way for a clearer understanding of the unique properties of tubulin that allow its varied functions within the cell. Some of the ongoing work on tubulin can be interpreted in terms of its structure, which can serve to guide future studies.

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Year:  1998        PMID： 9914260     DOI： 10.1016/s0959-440x(98)80099-7

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN： 0959-440X            Impact factor:   6.809


  43 in total

1.  Tau induces cooperative Taxol binding to microtubules.

Authors:  Jennifer L Ross; Christian D Santangelo; Victoria Makrides; D Kuchnir Fygenson
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-23       Impact factor: 11.205

2.  Anisotropic elastic network modeling of entire microtubules.

Authors:  Marco A Deriu; Monica Soncini; Mario Orsi; Mishal Patel; Jonathan W Essex; Franco M Montevecchi; Alberto Redaelli
Journal:  Biophys J       Date:  2010-10-06       Impact factor: 4.033

3.  Phosphoproteome analysis of the human mitotic spindle.

Authors:  Marjaana Nousiainen; Herman H W Silljé; Guido Sauer; Erich A Nigg; Roman Körner
Journal:  Proc Natl Acad Sci U S A       Date:  2006-03-24       Impact factor: 11.205

4.  Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents.

Authors:  Romeo Romagnoli; Pier Giovanni Baraldi; Carlota Lopez-Cara; Maria Kimatrai Salvador; Delia Preti; Mojgan Aghazadeh Tabrizi; Jan Balzarini; Peter Nussbaumer; Marcella Bassetto; Andrea Brancale; Xian-Hua Fu; Jun Li; Su-Zhan Zhang; Ernest Hamel; Roberta Bortolozzi; Giuseppe Basso; Giampietro Viola
Journal:  Bioorg Med Chem       Date:  2013-12-24       Impact factor: 3.641

5.  Effects of Visible-Light Irradiation of Protoporphyrin IX on the Self-Assembly of Tubulin Heterodimers.

Authors:  Alicia Vall-Sagarra; Brady McMicken; Santi Nonell; Lorenzo Brancaleon
Journal:  Chemphyschem       Date:  2016-08-30       Impact factor: 3.102

Review 6.  Microtubule drugs: action, selectivity, and resistance across the kingdoms of life.

Authors:  V Dostál; L Libusová
Journal:  Protoplasma       Date:  2014-03-21       Impact factor: 3.356

7.  Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.

Authors:  Romeo Romagnoli; Pier Giovanni Baraldi; Maria Kimatrai Salvador; Filippo Prencipe; Carlota Lopez-Cara; Santiago Schiaffino Ortega; Andrea Brancale; Ernest Hamel; Ignazio Castagliuolo; Stefania Mitola; Roberto Ronca; Roberta Bortolozzi; Elena Porcù; Giuseppe Basso; Giampietro Viola
Journal:  J Med Chem       Date:  2015-03-26       Impact factor: 7.446

8.  Relating molecular flexibility to function: a case study of tubulin.

Authors:  Ozlem Keskin; Stewart R Durell; Ivet Bahar; Robert L Jernigan; David G Covell
Journal:  Biophys J       Date:  2002-08       Impact factor: 4.033

9.  Modulation of host microtubule dynamics by pathogenic bacteria.

Authors:  Girish K Radhakrishnan; Gary A Splitter
Journal:  Biomol Concepts       Date:  2012-12-01

10.  Cytoskeletal changes in Eimeria bovis-infected host endothelial cells during first merogony.

Authors:  Carlos Hermosilla; Elmar Schröpfer; Michael Stowasser; Ursula Eckstein-Ludwig; Jan Hillern Behrendt; Horst Zahner
Journal:  Vet Res Commun       Date:  2008-07-31       Impact factor: 2.459
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