Literature DB >> 99023

Hepatitis B vaccines. On the threshold.

R H Purcell, J L Gerin.   

Abstract

Experimental hepatitis B vaccines have recently been developed and are undergoing preliminary evaluation. These vaccines are unique in that they are prepared from viral antigen purified from the plasmas of human chronic carriers because hepatitis B virus has not been cultivated in vitro. They appear to be safe and antigenic, but care must be exercised in their evaluation because of the potential risks inherent in all vaccines.

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Year:  1978        PMID： 99023

Source DB:  PubMed          Journal:  Am J Clin Pathol        ISSN： 0002-9173            Impact factor:   2.493


  10 in total

1.  Antigenic analysis of woodchuck hepatitis virus surface antigen with site-specific radioimmunoassays.

Authors:  P J Cote; R E Engle; C A Langer; A Ponzetto; J L Gerin
Journal:  J Virol       Date:  1984-03       Impact factor: 5.103

2.  Synthesis of antibodies to hepatitis B virus by cultured lymphocytes from chronic hepatitis B surface antigen carriers.

Authors:  G M Dusheiko; J H Hoofnagle; W G Cooksley; S P James; E A Jones
Journal:  J Clin Invest       Date:  1983-05       Impact factor: 14.808

3.  Novel and frequent mutations of hepatitis B virus coincide with a major histocompatibility complex class I-restricted T-cell epitope of the surface antigen.

Authors:  P C Tai; D Banik; G I Lin; S Pai; K Pai; M H Lin; G Yuoh; S Che; S H Hsu; T C Chen; T T Kuo; C S Lee; C S Yang; C Shih
Journal:  J Virol       Date:  1997-06       Impact factor: 5.103

4.  Serological markers for hepatitis types A and B among U.S. Arym soldiers, Germany.

Authors:  J J James; L Smith
Journal:  Am J Public Health       Date:  1979-12       Impact factor: 9.308

5.  Public knowledge about hepatitis B-related issues in Korea.

Authors:  C Chrusch; G Minuk
Journal:  Can J Infect Dis       Date:  1996-01

6.  Cell-mediated immunity to hepatitis B surface antigen in man.

Authors:  R G Hanson; J H Hoofnagle; G Y Minuk; R H Purcell; J L Gerin
Journal:  Clin Exp Immunol       Date:  1984-08       Impact factor: 4.330

7.  Perinatal transmission of hepatitis B virus.

Authors:  R K Chaudhary
Journal:  Can Med Assoc J       Date:  1983-03-15       Impact factor: 8.262

8.  Nonoverlapping antigenic sites of woodchuck hepatitis virus surface antigen and their cross-reactivity with ground squirrel hepatitis virus and hepatitis B virus surface antigens.

Authors:  P J Cote; J L Gerin
Journal:  J Virol       Date:  1983-07       Impact factor: 5.103

9.  Chemically synthesized peptides of hepatitis B surface antigen duplicate the d/y specificities and induce subtype-specific antibodies in chimpanzees.

Authors:  J L Gerin; H Alexander; J W Shih; R H Purcell; G Dapolito; R Engle; N Green; J G Sutcliffe; T M Shinnick; R A Lerner
Journal:  Proc Natl Acad Sci U S A       Date:  1983-04       Impact factor: 11.205

10.  Immunization of chimpanzees with hepatitis B virus-derived polypeptides.

Authors:  G R Dreesman; F B Hollinger; Y Sanchez; P Oefinger; J L Melnick
Journal:  Infect Immun       Date:  1981-04       Impact factor: 3.441
  10 in total

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