| Literature DB >> 990031 |
Abstract
Chloroquine compounds are known to cause a retinopathy which typically begins in the central fundus giving rise to a "bull's eye" macula. Ultimately peripheral changes may become apparent. In the routine eye examination of such patients emphasis has been laid on the central area of the fundus. A case is presented where the retinopathy was not diagnosed until marked peripheral changes had occurred with peripheral pigment changes, attenuated retinal vessels, slight optic atrophy, peripheral visual field restriction and a subnormal electroretinogram. The typical "bull's eye" changes were not apparent. Routine examination of the peripheral fundus by means of ophthalmoscopy and perimetry is necessary to avoid missing any such retinopathy.Entities:
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Year: 1976 PMID: 990031 DOI: 10.1111/j.1755-3768.1976.tb01802.x
Source DB: PubMed Journal: Acta Ophthalmol (Copenh) ISSN: 0001-639X