Literature DB >> 989860

Contaminated aqueous benzalkonium chloride. An unnecessary hospital infection hazard.

M J Frank, W Schaffner.   

Abstract

During January and February 1975, nine patients on a single ward of a rural Tennessee hospital unexpectedly developed sepsis. The aseptic technique employed in the management of intravenous infusions was implicated. Pseudomonas cepacia was recovered from the following: bloodstream, inuse intravenous infusions and the antiseptic, aqueous benzalkonium chloride. The outbreak again calls attention to the infection risk associated with the use of this product. Selection of less hazardous antiseptics and disinfectants is strongly recommended.

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Year:  1976        PMID: 989860

Source DB:  PubMed          Journal:  JAMA        ISSN: 0098-7484            Impact factor:   56.272


  15 in total

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Review 2.  Outbreaks associated with contaminated antiseptics and disinfectants.

Authors:  David J Weber; William A Rutala; Emily E Sickbert-Bennett
Journal:  Antimicrob Agents Chemother       Date:  2007-10-01       Impact factor: 5.191

3.  Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America.

Authors:  Leonard A Mermel; Michael Allon; Emilio Bouza; Donald E Craven; Patricia Flynn; Naomi P O'Grady; Issam I Raad; Bart J A Rijnders; Robert J Sherertz; David K Warren
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4.  Biocide susceptibility of the Burkholderia cepacia complex.

Authors:  Helen Rose; Adam Baldwin; Christopher G Dowson; Eshwar Mahenthiralingam
Journal:  J Antimicrob Chemother       Date:  2009-01-18       Impact factor: 5.790

5.  Quantitative neutralization assay of fungicidal activity of disinfectants.

Authors:  B Terleckyj; D A Axler
Journal:  Antimicrob Agents Chemother       Date:  1987-05       Impact factor: 5.191

Review 6.  The epidemiology of nosocomial epidemic Pseudomonas cepacia infections.

Authors:  W J Martone; O C Tablan; W R Jarvis
Journal:  Eur J Epidemiol       Date:  1987-09       Impact factor: 8.082

7.  Cluster of postinjection abscesses related to corticosteroid injections and use of benzalkonium chloride.

Authors:  R K Olson; R E Voorhees; H E Eitzen; H Rolka; C M Sewell
Journal:  West J Med       Date:  1999-03

Review 8.  Benzalkonium Chlorides: Uses, Regulatory Status, and Microbial Resistance.

Authors:  Beatriz Merchel Piovesan Pereira; Ilias Tagkopoulos
Journal:  Appl Environ Microbiol       Date:  2019-06-17       Impact factor: 4.792

Review 9.  Pathogenesis of infections related to intravascular catheterization.

Authors:  D A Goldmann; G B Pier
Journal:  Clin Microbiol Rev       Date:  1993-04       Impact factor: 26.132

10.  Survival of Serratia marcescens in benzalkonium chloride and in multiple-dose medication vials: relationship to epidemic septic arthritis.

Authors:  A K Nakashima; A K Highsmith; W J Martone
Journal:  J Clin Microbiol       Date:  1987-06       Impact factor: 5.948

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