Literature DB >> 989421

Hemodynamic effects caused by i.v. administration of verapamil in healthy subjects.

M Vincenzi, P Allegri, S Gabaldo, P Maiolino, R Ometto.   

Abstract

The hemodynamic data obtained after rapid i.v. administration of verapamil (Isoptin) (7.5-12.5 mg) to 7 healthy subjects are presented and discussed. The drug caused an early and statistically significant increase in heart rate and output with concomitant decrease of blood pressure (mainly diatolic) and peripheral resistance. Negative inotropic effects were not observed by the decreased peripheral resistance probably masks any possible negative inotropic effects of the drug.

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Year:  1976        PMID: 989421

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


  6 in total

1.  Influence of slow calcium-channel blockade on the cardiovascular effects of coffee.

Authors:  P Smits; T Thien; A van 't Laar
Journal:  Eur J Clin Pharmacol       Date:  1986       Impact factor: 2.953

Review 2.  Calcium antagonists. Clinical use in the treatment of systemic hypertension.

Authors:  C Spivack; S Ocken; W H Frishman
Journal:  Drugs       Date:  1983-02       Impact factor: 9.546

Review 3.  New antiarrhythmic drugs: their place in therapy.

Authors:  D L Keefe; R E Kates; D C Harrison
Journal:  Drugs       Date:  1981-11       Impact factor: 9.546

4.  Hemodynamic effects of Ro 23-6152 in patients with essential hypertension.

Authors:  H B Folkers; J C van Zwienen; P Boer; C H Kleinbloesem; G G Geyskes
Journal:  Eur J Clin Pharmacol       Date:  1991       Impact factor: 2.953

5.  Comparison of the cardiovascular effects of trans-diclofurime with different types of calcium antagonists in conscious spontaneously hypertensive rats.

Authors:  M A Petty; A K Mir
Journal:  Br J Pharmacol       Date:  1988-08       Impact factor: 8.739

Review 6.  The haemodynamic effects of nifedipine, verapamil and diltiazem in patients with coronary artery disease. A review.

Authors:  A L Soward; G L Vanhaleweyk; P W Serruys
Journal:  Drugs       Date:  1986-07       Impact factor: 9.546

  6 in total

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