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Literature DB >> 9889096

Nuclear import: a tale of two sites.

Abstract

The recently determined crystal structure of a nuclear localization sequence receptor has revealed an exquisitely specific interaction between ligand and receptor, and explains how simple and complex nuclear localization signals can both be recognized specifically by the same molecule.

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Year: 1998 PMID： 9889096 DOI： 10.1016/s0960-9822(98)00010-4

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

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Cited

22 in total

1. Structural basis for Nup2p function in cargo release and karyopherin recycling in nuclear import.

Authors: Yoshiyuki Matsuura; Allison Lange; Michelle T Harreman; Anita H Corbett; Murray Stewart
Journal: EMBO J Date: 2003-10-15 Impact factor: 11.598

2. The dual-specificity phosphatase CDC14B bundles and stabilizes microtubules.

Authors: Hyekyung P Cho; Yie Liu; Marla Gomez; John Dunlap; Mike Tyers; Yisong Wang
Journal: Mol Cell Biol Date: 2005-06 Impact factor: 4.272

3. Nuclear import of Epstein-Barr virus nuclear antigen 1 mediated by NPI-1 (Importin alpha5) is up- and down-regulated by phosphorylation of the nuclear localization signal for which Lys379 and Arg380 are essential.

Authors: Ryo Kitamura; Toshihiro Sekimoto; Sayuri Ito; Shizuko Harada; Hideo Yamagata; Hisao Masai; Yoshihiro Yoneda; Kazuo Yanagi
Journal: J Virol Date: 2006-02 Impact factor: 5.103

Nuclear import: a tale of two sites.

1. Structural basis for Nup2p function in cargo release and karyopherin recycling in nuclear import.

2. The dual-specificity phosphatase CDC14B bundles and stabilizes microtubules.

3. Nuclear import of Epstein-Barr virus nuclear antigen 1 mediated by NPI-1 (Importin alpha5) is up- and down-regulated by phosphorylation of the nuclear localization signal for which Lys379 and Arg380 are essential.

4. The hypoxic regulator of sterol synthesis nro1 is a nuclear import adaptor.

5. RanBP3 contains an unusual nuclear localization signal that is imported preferentially by importin-alpha3.

6. Resolution of the nuclear localization mechanism of glycogen synthase kinase-3: functional effects in apoptosis.

7. Subcellular localization of feline immunodeficiency virus integrase and mapping of its karyophilic determinant.

8. Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alpha.

9. Regulation of Greatwall kinase by protein stabilization and nuclear localization.

10. Human RNPS1 and its associated factors: a versatile alternative pre-mRNA splicing regulator in vivo.