Pharmacokinetics and pharmacodynamics of outpatient intravenous antimicrobial therapy.

Outpatient intravenous antimicrobial therapy has been widely accepted over the past decade. Knowledge of both the pharmacokinetics of antimicrobials and the pharmacodynamics predictive of antimicrobial efficacy enables one to design reasonable outpatient intravenous regimens for most agents. This article summarizes current knowledge of the pharmacokinetics and pharmacodynamics of agents commonly used in outpatient intravenous treatment regimens.