Literature DB >> 9887530

Hierridin B and 2,4-dimethoxy-6-heptadecyl-phenol, secondary metabolites from the cyanobacterium Phormidium ectocarpi with antiplasmodial activity.

O Papendorf1, G M König, A D Wright.   

Abstract

Bioassay guided fractionation of the lipophilic extract of the marine cyanobacterium Phormidium ectocarpi yielded a new natural product hierridin B and the previously described compound 2,4-dimethoxy-6-heptadecyl-phenol. Both structures were secured by extensive spectroscopic analysis (1D and 2D NMR, MS, GC-MS, IR). The isolate (mixture) showed antiplasmodial activity towards Plasmodium falciparum.

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Year:  1998        PMID： 9887530     DOI： 10.1016/s0031-9422(98)00440-3

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  11 in total

Review 1.  Antiplasmodial marine natural products in the perspective of current chemotherapy and prevention of malaria: a review.

Authors:  Dominique Laurent; Francesco Pietra
Journal:  Mar Biotechnol (NY)       Date:  2006-03-30       Impact factor: 3.619

2.  Isolation and Characterization of Anaephenes A-C, Alkylphenols from a Filamentous Cyanobacterium ( Hormoscilla sp., Oscillatoriales).

Authors:  David Brumley; Kara A Spencer; Sarath P Gunasekera; Thomas Sauvage; Jason Biggs; Valerie J Paul; Hendrik Luesch
Journal:  J Nat Prod       Date:  2018-11-29       Impact factor: 4.050

3.  Antimalarial linear lipopeptides from a Panamanian strain of the marine cyanobacterium Lyngbya majuscula.

Authors:  Kerry L McPhail; Jhonny Correa; Roger G Linington; José Gonzalez; Eduardo Ortega-Barría; Todd L Capson; William H Gerwick
Journal:  J Nat Prod       Date:  2007-04-19       Impact factor: 4.050

Review 4.  Uncovering Potential Applications of Cyanobacteria and Algal Metabolites in Biology, Agriculture and Medicine: Current Status and Future Prospects.

Authors:  Rachana Singh; Parul Parihar; Madhulika Singh; Andrzej Bajguz; Jitendra Kumar; Samiksha Singh; Vijay P Singh; Sheo M Prasad
Journal:  Front Microbiol       Date:  2017-04-25       Impact factor: 5.640

5.  Differential Toxicity of Cyanobacteria Isolated from Marine Sponges towards Echinoderms and Crustaceans.

Authors:  Ana Regueiras; Sandra Pereira; Maria Sofia Costa; Vitor Vasconcelos
Journal:  Toxins (Basel)       Date:  2018-07-18       Impact factor: 4.546

6.  Bioprospecting Sponge-Associated Marine Cyanobacteria to Produce Bioactive Compounds.

Authors:  Despoina Konstantinou; Eleni Mavrogonatou; Sevasti-Kiriaki Zervou; Panagiotis Giannogonas; Spyros Gkelis
Journal:  Toxins (Basel)       Date:  2020-01-23       Impact factor: 4.546

7.  Genome Mining and Evolutionary Analysis Reveal Diverse Type III Polyketide Synthase Pathways in Cyanobacteria.

Authors:  Joachim Steen Larsen; Leanne Andrea Pearson; Brett Anthony Neilan
Journal:  Genome Biol Evol       Date:  2021-04-05       Impact factor: 3.416

8.  Chemoecological screening reveals high bioactivity in diverse culturable Portuguese marine cyanobacteria.

Authors:  Pedro N Leão; Vitor Ramos; Patrício B Gonçalves; Flávia Viana; Olga M Lage; William H Gerwick; Vitor M Vasconcelos
Journal:  Mar Drugs       Date:  2013-04-22       Impact factor: 5.118

9.  Antitumor activity of hierridin B, a cyanobacterial secondary metabolite found in both filamentous and unicellular marine strains.

Authors:  Pedro N Leão; Margarida Costa; Vitor Ramos; Alban R Pereira; Virgínia C Fernandes; Valentina F Domingues; William H Gerwick; Vitor M Vasconcelos; Rosário Martins
Journal:  PLoS One       Date:  2013-07-29       Impact factor: 3.240

Review 10.  Chemistry, bioactivity and biosynthesis of cyanobacterial alkylresorcinols.

Authors:  Teresa P Martins; Caroline Rouger; Nathaniel R Glasser; Sara Freitas; Nelly B de Fraissinette; Emily P Balskus; Deniz Tasdemir; Pedro N Leão
Journal:  Nat Prod Rep       Date:  2019-10-16       Impact factor: 13.423
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