Literature DB >> 9886687

Inhibition of anaesthetic-induced emesis by a NK1 or 5-HT3 receptor antagonist in the house musk shrew, Suncus murinus.

C Gardner1, M Perren.   

Abstract

The effects of a NK1 antagonist, GR205171, and a 5-HT3 antagonist, ondansetron, in a novel model of post-anaesthesia-induced emesis in Suncus murinus is described. GR205171 (1 and 3 mg k(-1) s.c) and ondansetron (3 mg kg(-1) s.c.) each significantly inhibited emesis. This model may be useful for studying drugs to treat post-operative nausea and vomiting in man.

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Year:  1998        PMID： 9886687     DOI： 10.1016/s0028-3908(98)00133-6

Source DB:  PubMed          Journal:  Neuropharmacology        ISSN： 0028-3908            Impact factor:   5.250


  10 in total

1.  Role of the abdominal vagus and hindbrain in inhalational anesthesia-induced vomiting.

Authors:  Ragini G Gupta; Claire Schafer; Yolande Ramaroson; Michael G Sciullo; Charles C Horn
Journal:  Auton Neurosci       Date:  2016-07-02       Impact factor: 3.145

2.  The effect of ondansetron in prevention of postoperative shivering after general anesthesia in gynecological surgery.

Authors:  M Entezari Asl; Kh Isazadehfar; G Akhavanakbari; M Khoshbaten
Journal:  Iran Red Crescent Med J       Date:  2012-05-30       Impact factor: 0.611

3.  Post-anesthesia vomiting: impact of isoflurane and morphine on ferrets and musk shrews.

Authors:  Charles C Horn; Kelly Meyers; Diana Pak; Allysa Nagy; Christian C Apfel; Brian A Williams
Journal:  Physiol Behav       Date:  2012-04-04

Review 4.  Potential of substance P antagonists as antiemetics.

Authors:  P Diemunsch; L Grélot
Journal:  Drugs       Date:  2000-09       Impact factor: 9.546

5.  Utilization of the least shrew as a rapid and selective screening model for the antiemetic potential and brain penetration of substance P and NK1 receptor antagonists.

Authors:  Nissar A Darmani; Yaozhi Wang; Joseph Abad; Andrew P Ray; Gerald R Thrush; Juan Ramirez
Journal:  Brain Res       Date:  2008-04-09       Impact factor: 3.252

Review 6.  Pathophysiological and neurochemical mechanisms of postoperative nausea and vomiting.

Authors:  Charles C Horn; William J Wallisch; Gregg E Homanics; John P Williams
Journal:  Eur J Pharmacol       Date:  2013-10-26       Impact factor: 4.432

Review 7.  Integration of vestibular and emetic gastrointestinal signals that produce nausea and vomiting: potential contributions to motion sickness.

Authors:  Bill J Yates; Michael F Catanzaro; Daniel J Miller; Andrew A McCall
Journal:  Exp Brain Res       Date:  2014-04-16       Impact factor: 1.972

Review 8.  [Postoperative nausea and vomiting].

Authors:  M R Tramèr
Journal:  Anaesthesist       Date:  2007-07       Impact factor: 1.041

9.  Identification of neural networks that contribute to motion sickness through principal components analysis of fos labeling induced by galvanic vestibular stimulation.

Authors:  Carey D Balaban; Sarah W Ogburn; Susan G Warshafsky; Abdul Ahmed; Bill J Yates
Journal:  PLoS One       Date:  2014-01-23       Impact factor: 3.240

10.  Prophylactic use of intravenous ondansetron versus ketamine - midazolam combination for prevention of shivering during spinal anesthesia: A randomized double-blind placebo-controlled trial.

Authors:  Mohammadreza Safavi; Azim Honarmand; Sara Mohammadsadeqie
Journal:  Adv Biomed Res       Date:  2015-09-28
  10 in total

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