Literature DB >> 9884019

Diversity and complexity of ceramide signalling in apoptosis.

T Okazaki1, T Kondo, T Kitano, M Tashima.   

Abstract

Sphingolipid ceramide has emerged as a lipid messenger of cell functions including differentiation and apoptosis. Diverse kinds of stresses (ultraviolet, irradiation, heat shock and hypoxia) and biological factors (TNF-alpha, IFN-gamma and Fas antibody) require ceramide generation to execute apoptosis. The review summarises the diversity and complexity of up- and downstream of ceramide signalling in apoptosis and clinical implications of ceramide-induced apoptosis.

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Year:  1998        PMID： 9884019     DOI： 10.1016/s0898-6568(98)00035-7

Source DB:  PubMed          Journal:  Cell Signal        ISSN： 0898-6568            Impact factor:   4.315


  18 in total

Review 1.  Current methods for the identification and quantitation of ceramides: an overview.

Authors:  A E Cremesti; A S Fischl
Journal:  Lipids       Date:  2000-09       Impact factor: 1.880

2.  Involvement of the acid sphingomyelinase pathway in uva-induced apoptosis.

Authors:  Y Zhang; P Mattjus; P C Schmid; Z Dong; S Zhong; W Y Ma; R E Brown; A M Bode; H H Schmid; Z Dong
Journal:  J Biol Chem       Date:  2001-01-22       Impact factor: 5.157

3.  Targeting glucosylceramide synthase sensitizes imatinib-resistant chronic myeloid leukemia cells via endogenous ceramide accumulation.

Authors:  Yusuf Baran; Jacek Bielawski; Ufuk Gunduz; Besim Ogretmen
Journal:  J Cancer Res Clin Oncol       Date:  2011-08-11       Impact factor: 4.553

4.  A novel sphingophosphonolipid head group 1-hydroxy-2-aminoethyl phosphonate in Bdellovibrio stolpii.

Authors:  Y Watanabe; M Nakajima; T Hoshino; K Jayasimhulu; E E Brooks; E S Kaneshiro
Journal:  Lipids       Date:  2001-05       Impact factor: 1.880

5.  TNF-α induced apoptosis is accompanied with rapid CD30 and slower CD45 shedding from K-562 cells.

Authors:  Vladimir Jurisic; Tatjana Srdic-Rajic; Gordana Konjevic; Gordana Bogdanovic; Mija Colic
Journal:  J Membr Biol       Date:  2011-01-11       Impact factor: 1.843

6.  DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells.

Authors:  Teka-Ann S Haynes; Valery Filippov; Maria Filippova; Jun Yang; Kangling Zhang; Penelope J Duerksen-Hughes
Journal:  Biochim Biophys Acta       Date:  2012-02-11

7.  Virion disassembly is required for apoptosis induced by reovirus.

Authors:  Jodi L Connolly; Terence S Dermody
Journal:  J Virol       Date:  2002-02       Impact factor: 5.103

8.  Ceramides: branched alkyl chains in the sphingolipid siblings of diacylglycerol improve biological potency.

Authors:  Ji-Hye Kang; Himanshu Garg; Dina M Sigano; Nicholas Francella; Robert Blumenthal; Victor E Marquez
Journal:  Bioorg Med Chem       Date:  2009-01-11       Impact factor: 3.641

9.  Complete structural characterization of ceramides as [M-H]- ions by multiple-stage linear ion trap mass spectrometry.

Authors:  Fong-Fu Hsu
Journal:  Biochimie       Date:  2016-08-12       Impact factor: 4.079

10.  Ceramide galactosyltransferase (UGT8) is a molecular marker of breast cancer malignancy and lung metastases.

Authors:  P Dzięgiel; T Owczarek; E Plazuk; A Gomułkiewicz; M Majchrzak; M Podhorska-Okołów; K Driouch; R Lidereau; M Ugorski
Journal:  Br J Cancer       Date:  2010-07-20       Impact factor: 7.640
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