OBJECTIVE: To evaluate our experience with primary carcinomas of the female urethra, by analysing the impact of tumour variables and treatment on overall, disease-specific, local recurrence- and metastasis-free survival. PATIENTS AND METHODS: Between 1958 and 1994, 72 women (median age 60 years, mean 59, range 21-84) with primary urethral carcinoma were identified. They were followed for a median (range) of 85 (0-384) months. The patients were stratified by stage, nodal status, histology, treatment, type of surgery, site of disease, year of diagnosis and smoking habit. RESULTS: In a univariate analysis, stage, nodal status, type of surgery and site of the disease were important factors for survival and recurrence. In a multivariate analysis, primary stage, nodal status and site of disease were independent predictors of survival. CONCLUSION: Current modalities of treatment are ineffective for local control and survival; new treatment strategies are needed for female urethral cancers.
OBJECTIVE: To evaluate our experience with primary carcinomas of the female urethra, by analysing the impact of tumour variables and treatment on overall, disease-specific, local recurrence- and metastasis-free survival. PATIENTS AND METHODS: Between 1958 and 1994, 72 women (median age 60 years, mean 59, range 21-84) with primary urethral carcinoma were identified. They were followed for a median (range) of 85 (0-384) months. The patients were stratified by stage, nodal status, histology, treatment, type of surgery, site of disease, year of diagnosis and smoking habit. RESULTS: In a univariate analysis, stage, nodal status, type of surgery and site of the disease were important factors for survival and recurrence. In a multivariate analysis, primary stage, nodal status and site of disease were independent predictors of survival. CONCLUSION: Current modalities of treatment are ineffective for local control and survival; new treatment strategies are needed for female urethral cancers.
Authors: Joris W Derksen; Otto Visser; Guy Brutel de la Rivière; Eric J Meuleman; Eddi A Heldeweg; Brunolf W Lagerveld Journal: World J Urol Date: 2012-05-22 Impact factor: 4.226
Authors: Roy Mano; Emily A Vertosick; Joseph Sarcona; Daniel D Sjoberg; Nicole E Benfante; Timothy F Donahue; Harry W Herr; S Machele Donat; Bernard H Bochner; Guido Dalbagni; Alvin C Goh Journal: BJU Int Date: 2020-06-04 Impact factor: 5.588
Authors: Mierxiati Abudurexiti; Jun Wang; Ning Shao; Fang-Ning Wan; Yao Zhu; Bo Dai; Ding-Wei Ye Journal: Cancer Manag Res Date: 2018-12-07 Impact factor: 3.989