Literature DB >> 9882524

Generation of carboxy-terminally deleted forms of STAT5 during preparation of cell extracts.

K Garimorth1, T Welte, W Doppler.   

Abstract

Carboxy-terminally deleted forms of STAT5 have been described to be generated in vivo either by proteolytic processing or by differential splicing mechanisms. By comparing two different cell extraction procedures, we can show that in the mammary gland carboxy-terminally deleted forms are produced in vitro and are not detectable in extracts prepared by SDS lysis. Copyright 1999 Academic Press.

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Year:  1999        PMID: 9882524     DOI: 10.1006/excr.1998.4289

Source DB:  PubMed          Journal:  Exp Cell Res        ISSN: 0014-4827            Impact factor:   3.905


  2 in total

1.  N-terminal truncation of Stat5a/b circumvents PIAS3-mediated transcriptional inhibition of Stat5 in prostate cancer cells.

Authors:  Ayush Dagvadorj; Shyh-Han Tan; Zhiyong Liao; Jianwu Xie; Martti Nurmi; Kalle Alanen; Hallgeir Rui; Tuomas Mirtti; Marja T Nevalainen
Journal:  Int J Biochem Cell Biol       Date:  2010-09-18       Impact factor: 5.085

2.  STAT5 isoforms: controversies and clarifications.

Authors:  Haydeé L Ramos; John J O'Shea; Wendy T Watford
Journal:  Biochem J       Date:  2007-05-15       Impact factor: 3.857

  2 in total

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