Literature DB >> 9881759

Conjugation of 5-azido-3-oxapentyl glycosides with thiolated proteins through the use of thiophilic derivatives.

V Fernández-Santana1, R González-Lio, J Sarracent-Pérez, V Verez-Bencomo.   

Abstract

5-Azido-3-oxa-pentyl beta-D-galactopyranoside was prepared from diethylene glycol monochlorohydrin and used as a model of oligosaccharide hapten. After deprotection, a series of amides bearing thiophilic groups had been obtained through the terminal amino function and essayed in coupling reactions with thiolated BSA. Also several Lewis human blood group oligosaccharides had been conjugated with thiolated BSA demonstrating the usefulness of the methodology.

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Year:  1998        PMID： 9881759     DOI： 10.1023/a:1006903524007

Source DB:  PubMed          Journal:  Glycoconj J        ISSN： 0282-0080            Impact factor:   2.916


  8 in total

1.  A colorimetric method for determining low concentrations of mercaptans.

Authors:  G L ELLMAN
Journal:  Arch Biochem Biophys       Date:  1958-04       Impact factor: 4.013

2.  Glycosides of 8-hydroxy-3,6-dioxaoctanal. A synthesis of a new spacer for synthetic oligosaccharides.

Authors:  V Verez-Bencomo; M T Campos-Valdes; J R Mariño-Albernas; V Fernandez-Santana; M Hernandez-Rensoli; C S Perez-Martinez
Journal:  Carbohydr Res       Date:  1991-09-18       Impact factor: 2.104

3.  Synthetic trimer and tetramer of 3-beta-D-ribose-(1-1)-D-ribitol-5-phosphate conjugated to protein induce antibody responses to Haemophilus influenzae type b capsular polysaccharide in mice and monkeys.

Authors:  C C Peeters; D Evenberg; P Hoogerhout; H Käyhty; L Saarinen; C A van Boeckel; G A van der Marel; J H van Boom; J T Poolman
Journal:  Infect Immun       Date:  1992-05       Impact factor: 3.441

4.  Preparation and some properties of maleimido acids and maleoyl derivatives of peptides.

Authors:  O Keller; J Rudinger
Journal:  Helv Chim Acta       Date:  1975-03-12       Impact factor: 2.164

5.  A method for glycoconjugate synthesis.

Authors:  V Pozsgay
Journal:  Glycoconj J       Date:  1993-04       Impact factor: 2.916

6.  Immunization of breast cancer patients using a synthetic sialyl-Tn glycoconjugate plus Detox adjuvant.

Authors:  G D MacLean; M Reddish; R R Koganty; T Wong; S Gandhi; M Smolenski; J Samuel; J M Nabholtz; B M Longenecker
Journal:  Cancer Immunol Immunother       Date:  1993       Impact factor: 6.968

7.  Hybridomas specific for carbohydrates; synthetic human blood group antigens for the production, selection, and characterization of monoclonal typing reagents.

Authors:  D R Bundle; M A Gidney; N Kassam; A F Rahman
Journal:  J Immunol       Date:  1982-08       Impact factor: 5.422

8.  Streptococcus pneumoniae type XIV polysaccharide: synthesis of a repeating branched tetrasaccharide with dioxa-type spacer-arms.

Authors:  P H Amvam-Zollo; P Sinaÿ
Journal:  Carbohydr Res       Date:  1986-08-01       Impact factor: 2.104
  8 in total
  2 in total

1.  The potential of dextran-based glycoconjugates for development of Helicobacter pylori vaccine.

Authors:  Eleonora Altman; Vandana Chandan; Blair Harrison
Journal:  Glycoconj J       Date:  2013-08-30       Impact factor: 2.916

2.  Synthetic teichoic acid conjugate vaccine against nosocomial Gram-positive bacteria.

Authors:  Diana Laverde; Dominique Wobser; Felipe Romero-Saavedra; Wouter Hogendorf; Gijsbert van der Marel; Martin Berthold; Andrea Kropec; Jeroen Codee; Johannes Huebner
Journal:  PLoS One       Date:  2014-10-21       Impact factor: 3.240
  2 in total

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