Literature DB >> 9881465

BSE in Northern Ireland: epidemiological patterns past, present and future.

N M Ferguson1, A C Ghani, C A Donnelly, G O Denny, R M Anderson.   

Abstract

By 30 January 1998, there had been 170,259 confirmed cases of BSE in Great Britain (GB), 1766 confirmed cases in Northern Ireland (NI) (2 January 1998), and 276 confirmed cases in the Republic of Ireland (31 January 1998). Analysis of the epidemiological patterns in the NI epidemic reveals significant clustering of cases in herds and counties. The observed clustering of cases within herds results in lower per capita incidence of BSE in previously unaffected herds, providing support for the introduction of a certified herd scheme in NI. By fitting a backcalculation model to the case data, we can estimate the number of animals infected with the aetiological agent of BSE and project the number of future cases. We predict that the epidemic will decline rapidly, with approximately 99 cases (95% confidence interval 30,504) occurring in the five year period 1997-2001.

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Year:  1998        PMID: 9881465      PMCID: PMC1689017          DOI: 10.1098/rspb.1998.0329

Source DB:  PubMed          Journal:  Proc Biol Sci        ISSN: 0962-8452            Impact factor:   5.349


  13 in total

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4.  Epidemiology of bovine spongiform encephalopathy in Northern Ireland 1988 to 1995.

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Journal:  Vet Rec       Date:  1997-03-22       Impact factor: 2.695

5.  Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

Authors:  J Collinge; K C Sidle; J Meads; J Ironside; A F Hill
Journal:  Nature       Date:  1996-10-24       Impact factor: 49.962

6.  Molecular assessment of the potential transmissibilities of BSE and scrapie to humans.

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Journal:  Nature       Date:  1997-07-17       Impact factor: 49.962

7.  Bovine spongiform encephalopathy in Northern Ireland: epidemiological observations 1988-1990.

Authors:  G O Denny; J W Wilesmith; R A Clements; W D Hueston
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8.  Analysis of dam-calf pairs of BSE cases: confirmation of a maternal risk enhancement.

Authors:  C A Donnelly; N M Ferguson; A C Ghani; J W Wilesmith; R M Anderson
Journal:  Proc Biol Sci       Date:  1997-11-22       Impact factor: 5.349

9.  Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent.

Authors:  M E Bruce; R G Will; J W Ironside; I McConnell; D Drummond; A Suttie; L McCardle; A Chree; J Hope; C Birkett; S Cousens; H Fraser; C J Bostock
Journal:  Nature       Date:  1997-10-02       Impact factor: 49.962

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Authors:  R G Will; J W Ironside; M Zeidler; S N Cousens; K Estibeiro; A Alperovitch; S Poser; M Pocchiari; A Hofman; P G Smith
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Authors:  James O Lloyd-Smith; Dylan George; Kim M Pepin; Virginia E Pitzer; Juliet R C Pulliam; Andrew P Dobson; Peter J Hudson; Bryan T Grenfell
Journal:  Science       Date:  2009-12-04       Impact factor: 47.728

3.  vCJD risk in the Republic of Ireland.

Authors:  Michael S Harney; Azra C Ghani; C A Donnelly; Rory McConn Walsh; Michael Walsh; Rachel Howley; Francesca Brett; Michael Farrell
Journal:  BMC Infect Dis       Date:  2003-11-26       Impact factor: 3.090

  3 in total

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