Literature DB >> 987924

Increased aggression in rats after withdrawal of long term used oxazepam.

Z S Herman, A Drybański, H I Trzeciak.   

Abstract

The withdrawal of oxazepam (5 mg/kg i.p.) applied for 1 year in rats, increased shock-induced aggression of animals. This phenomenon is interpreted as a sign of abstinence and suggests that long-term treatment causes dependence to oxazepam in rats.

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Year:  1976        PMID： 987924     DOI： 10.1007/bf01953107

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  7 in total

Review 1.  A critical review of oxazepam: efficacy and specificity.

Authors:  B Blackwell
Journal:  Dis Nerv Syst       Date:  1975-05

2.  RELATIVE POTENCIES OF BENZODIAZEPINES AS MEASURED BY THEIR EFFECTS ON CONFLICT BEHAVIOR.

Authors:  I GELLER
Journal:  Arch Int Pharmacodyn Ther       Date:  1964-05-01

3.  Oxazepam, prazepam, and aggression in mice.

Authors:  K A Fox; F J Guerriero; D C Zanghi
Journal:  Pharmacol Res Commun       Date:  1974-06

4.  Conflict behavior in a heated-floor maze: effects of oxazepam.

Authors:  P Soubrié; L Schoonhoed; P Simon; J R Boissier
Journal:  Psychopharmacologia       Date:  1972

5.  [Pharmacologic effects of 7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one].

Authors:  H Klupp; J Kähling
Journal:  Arzneimittelforschung       Date:  1965-04

6.  Effect of subcortical lesions on shock-induced aggression in the rat.

Authors:  B S Eichelman
Journal:  J Comp Physiol Psychol       Date:  1971-03

7.  Effects of various drugs on 3,4-dihydroxyphenylalanine (DL-DOPA)-induced excitation (agressive behavior) in mice.

Authors:  H C Yen; M H Katz; S Krop
Journal:  Toxicol Appl Pharmacol       Date:  1970-11       Impact factor: 4.219
  7 in total

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