| Literature DB >> 9878859 |
J C Fowler1, L D Partridge, L Gervitz.
Abstract
The nitric oxide donor hydroxylamine (NH2OH) induced a transient depression of the evoked synaptic potential recorded in the rat hippocampal CA1 region. This depression was abolished with an adenosine A1 antagonist, 8-cyclopentyltheophylline. In addition, hydroxylamine reversed adenosine A1 receptor-mediated inhibition of the evoked population spike, the fEPSP and the intracellularly recorded EPSP. The inhibitory modulation of adenosine A1 receptor activation by hydroxylamine suggests the presence of a potent endogenous regulatory site. Copyright 1999 Elsevier Science B.V.Entities:
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Year: 1999 PMID： 9878859 DOI： 10.1016/s0006-8993(98)01114-7
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252