Literature DB >> 9878516

Genetic analysis of dystrophic cardiac calcification in DBA/2 mice.

F A van den Broek1, R Bakker, M den Bieman, A X Fielmich-Bouwman, A G Lemmens, H A van Lith, I Nissen, J M Ritskes-Hoitinga, G van Tintelen, L F van Zutphen.   

Abstract

A DBA/2 x D2B6F1 backcross was produced in order to study the genetic background of pathological soft tissue calcification in the mouse. Calcification was assessed in the myocardium, kidney and tongue. Significant co-segregation was found with the genotype of microsatellite markers on the proximal end of Chromosome 7. This region contains a candidate gene, Hrc, coding for the histidine-rich calcium binding protein in the sarcoplasmatic reticulum. The results support the hypothesis that the gene previously reported to be responsible for DCC (dystrophic cardiac calcification) in C3H mice (1) causes generalized soft tissue calcification in DBA/2 mice. Copyright 1998 Academic Press.

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Year:  1998        PMID： 9878516     DOI： 10.1006/bbrc.1998.9776

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  9 in total

Review 1.  Histidine-rich calcium binding protein: the new regulator of sarcoplasmic reticulum calcium cycling.

Authors:  Demetrios A Arvanitis; Elizabeth Vafiadaki; Despina Sanoudou; Evangelia G Kranias
Journal:  J Mol Cell Cardiol       Date:  2010-08-31       Impact factor: 5.000

2.  Compensated hypertrophy of cardiac ventricles in aged transgenic FVB/N mice overexpressing calsequestrin.

Authors:  Yoji Sato; Albrecht G Schmidt; Helen Kiriazis; Brian D Hoit; Evangelia G Kranias
Journal:  Mol Cell Biochem       Date:  2003-01       Impact factor: 3.396

3.  A Reproducible Mouse Model of Moderate CKD With Early Manifestations of Osteoblastic Transition of Cardiovascular System.

Authors:  Sarah E Machado; Daryll Spangler; Laurence M Black; Amie M Traylor; József Balla; Abolfazl Zarjou
Journal:  Front Physiol       Date:  2022-04-29       Impact factor: 4.755

Review 4.  The emerging role of phosphate in vascular calcification.

Authors:  Cecilia M Giachelli
Journal:  Kidney Int       Date:  2009-01-14       Impact factor: 10.612

5.  Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomics.

Authors:  Haijin Meng; Iset Vera; Nam Che; Xuping Wang; Susanna S Wang; Leslie Ingram-Drake; Eric E Schadt; Thomas A Drake; Aldons J Lusis
Journal:  Proc Natl Acad Sci U S A       Date:  2007-03-06       Impact factor: 11.205

6.  PiT-2, a type III sodium-dependent phosphate transporter, protects against vascular calcification in mice with chronic kidney disease fed a high-phosphate diet.

Authors:  Shunsuke Yamada; Elizabeth M Leaf; Jia Jun Chia; Timothy C Cox; Mei Y Speer; Cecilia M Giachelli
Journal:  Kidney Int       Date:  2018-07-21       Impact factor: 10.612

7.  A locus on chromosome 7 determines dramatic up-regulation of osteopontin in dystrophic cardiac calcification in mice.

Authors:  Zouhair Aherrahrou; Susanne B Axtner; Piotr M Kaczmarek; Alexandra Jurat; Susanne Korff; Lars C Doehring; Dieter Weichenhan; Hugo A Katus; Boris T Ivandic
Journal:  Am J Pathol       Date:  2004-04       Impact factor: 4.307

Review 8.  X-ray Micro-Computed Tomography: An Emerging Technology to Analyze Vascular Calcification in Animal Models.

Authors:  Samantha J Borland; Julia Behnsen; Nick Ashton; Sheila E Francis; Keith Brennan; Michael J Sherratt; Philip J Withers; Ann E Canfield
Journal:  Int J Mol Sci       Date:  2020-06-25       Impact factor: 5.923

Review 9.  The Histidine-Rich Calcium Binding Protein in Regulation of Cardiac Rhythmicity.

Authors:  Demetrios A Arvanitis; Elizabeth Vafiadaki; Daniel M Johnson; Evangelia G Kranias; Despina Sanoudou
Journal:  Front Physiol       Date:  2018-09-27       Impact factor: 4.566
  9 in total

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