Literature DB >> 9877534

Effect of aluminum on superoxide dismutase activity in the adult rat brain.

F Atienzar1, D Desor, D Burnel, J M Keller, P Lehr, P Vasseur.   

Abstract

Male rats were treated daily with an intraperitoneal injection of 15 mg aluminum (Al chloride)/kg body weight for 17 d, in order to study the effects on superoxide dismutase (SOD) activities in the brain (cortex). No significant difference between control and treated animals was registered in the Cu/Zn and Mn SOD activities in the gray matter of the cortex. High Al levels were found in the plasma, the spleen, and the liver of the treated animals in comparison to the controls, but not in the cortex homogenates (gray matter). In addition, Al induced a significant decrease in food ingestion and weight gain.

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Year:  1998        PMID: 9877534     DOI: 10.1007/BF02784111

Source DB:  PubMed          Journal:  Biol Trace Elem Res        ISSN: 0163-4984            Impact factor:   3.738


  1 in total

1.  Quercetin and omega 3 ameliorate oxidative stress induced by aluminium chloride in the brain.

Authors:  Haytham Abdallah Ali; Mohamed Afifi; Aaser Mohamed Abdelazim; Yahia Youssef Mosleh
Journal:  J Mol Neurosci       Date:  2014-02-01       Impact factor: 3.444

  1 in total

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