Literature DB >> 9875480

Studies of structure activity relationship of flavonoids for the anti-allergic actions.

H Cheong1, S Y Ryu, M H Oak, S H Cheon, G S Yoo, K M Kim.   

Abstract

The structure activity relationship of flavonoids for anti-allergic actions was studied by determining the IC50 values for the degranulation. The hexosaminidase release from RBL-2H3 cells (degranulation marker) was employed as an estimate for the anti-allergic actions. Among 22 flavonoid compounds tested, luteolin, apigenin, diosmetin, fisetin, and quercetin were found to be most active with IC50 values less than 10 microM.

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Year:  1998        PMID： 9875480     DOI： 10.1007/bf02974647

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  17 in total

Review 1.  A review on pharmacological and analytical aspects of diosmetin: a concise report.

Authors:  Kanika Patel; Manoj Gadewar; Vijay Tahilyani; Dinesh Kumar Patel
Journal:  Chin J Integr Med       Date:  2013-10-04       Impact factor: 1.978

Review 2.  Biological activities of extracts from Chinese bayberry (Myrica rubra Sieb. et Zucc.): a review.

Authors:  Chongde Sun; Huizhong Huang; Changjie Xu; Xian Li; Kunsong Chen
Journal:  Plant Foods Hum Nutr       Date:  2013-06       Impact factor: 3.921

3.  Fisetin averts oxidative stress in pancreatic tissues of streptozotocin-induced diabetic rats.

Authors:  Gopalan Sriram Prasath; Chinnakrishnan Shanmuga Sundaram; Sorimuthu Pillai Subramanian
Journal:  Endocrine       Date:  2013-01-01       Impact factor: 3.633

4.  Hydroxyl Groups on Annular Ring-B Dictate the Affinities of Flavonol-CCL2 Chemokine Binding Interactions.

Authors:  Nidhi Joshi; Deepak Kumar Tripathi; Nupur Nagar; Krishna Mohan Poluri
Journal:  ACS Omega       Date:  2021-04-06

5.  Role of phenolic compounds in peptic ulcer: An overview.

Authors:  Sabiha Sumbul; Mohd Aftab Ahmad; Asif Mohd; Akhtar Mohd
Journal:  J Pharm Bioallied Sci       Date:  2011-07

6.  Protective effects of flavonol isoquercitrin, against 6-hydroxy dopamine (6-OHDA)-induced toxicity in PC12 cells.

Authors:  Kasthuri Bai Magalingam; Ammu Radhakrishnan; Nagaraja Haleagrahara
Journal:  BMC Res Notes       Date:  2014-01-21

7.  Selaginella tamariscina extract suppresses TPA-induced invasion and metastasis through inhibition of MMP-9 in human nasopharyngeal carcinoma HONE-1 cells.

Authors:  Chung-Han Hsin; Buor-Chang Wu; Chun-Yi Chuang; Shun-Fa Yang; Yi-Hsien Hsieh; Hsin-Yu Ho; Huang-Pin Lin; Mu-Kuan Chen; Chiao-Wen Lin
Journal:  BMC Complement Altern Med       Date:  2013-09-23       Impact factor: 3.659

8.  Iminoflavones combat 1,2-dimethyl hydrazine-induced aberrant crypt foci development in colon cancer.

Authors:  V Ganga Prasad; Shishir Kawade; B S Jayashree; Neetinkumar D Reddy; Albi Francis; Pawan G Nayak; Anoop Kishore; K Nandakumar; C Mallikarjuna Rao; Rekha R Shenoy
Journal:  Biomed Res Int       Date:  2014-06-05       Impact factor: 3.411

9.  Fisetin inhibits hyperglycemia-induced proinflammatory cytokine production by epigenetic mechanisms.

Authors:  Hye Joo Kim; Seong Hwan Kim; Jung-Mi Yun
Journal:  Evid Based Complement Alternat Med       Date:  2012-12-20       Impact factor: 2.629

Review 10.  Flavonoids and asthma.

Authors:  Toshio Tanaka; Ryo Takahashi
Journal:  Nutrients       Date:  2013-06-10       Impact factor: 5.717
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