Literature DB >> 98748

[Immuno-electro-diffusion on cellulose acetate membrane for serological testing in human malaria (author's transl)].

P Druilhe, L Monjour, D Richard-Lenoble, M Gentilini.   

Abstract

An immuno-electro-diffusion assay for human malaria, using cellulose acetate gel, is described. More than 3500 sera have been tested by this method, which proved very useful for epidemiology since 400 sera a day can be tested by one person, with simple equipment. Its sensitivity compared well to the IFA test, although the antibodies revealed are quite different. A constnat precipitin line appeared, against 56 degrees C labile antigens, in sera of subjects infected by P. falciparum, and up to 8 other precipitins per serum tested. The test may be useful in analyzing these multiple antibodies occurring in patients with malaria.

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Year:  1978        PMID: 98748

Source DB:  PubMed          Journal:  Pathol Biol (Paris)        ISSN: 0369-8114


  3 in total

1.  Epidemiological correlation between levels of antibodies promoting merozoite phagocytosis of Plasmodium falciparum and malaria-immune status.

Authors:  P Druilhe; S Khusmith
Journal:  Infect Immun       Date:  1987-04       Impact factor: 3.441

2.  Impairment of Plasmodium falciparum-specific antibody response in severe malaria.

Authors:  P Brasseur; J J Ballet; P Druilhe
Journal:  J Clin Microbiol       Date:  1990-02       Impact factor: 5.948

3.  Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytes.

Authors:  H Bouharoun-Tayoun; P Attanath; A Sabchareon; T Chongsuphajaisiddhi; P Druilhe
Journal:  J Exp Med       Date:  1990-12-01       Impact factor: 14.307

  3 in total

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