Literature DB >> 9874677

Streptococcal DNase B is immunologically identical to superantigen SpeF but involves separate domains.

A Eriksson1, B Eriksson, S E Holm, M Norgren.   

Abstract

The previous suggestion that streptococcal superantigen SpeF might be identical to DNase B was confirmed in this study. Polyclonal SpeF-specific antisera were able to inhibit depolymerization of methyl-green DNA by DNase B. However, T-cell mitogenicity and nuclease activity appear to involve separate immune epitopes on SpeF, since sera with the capacity to neutralize the mitogenic activity of SpeF did not always inhibit the DNase activity.

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Year:  1999        PMID： 9874677      PMCID： PMC95673          DOI： 10.1128/CDLI.6.1.133-136.1999

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN： 1071-412X


  21 in total

1.  Virulence properties of erysipelas-associated group A streptococci.

Authors:  A Norrby; B Eriksson; M Norgren; C J Rönström; A C Sjöblom; K Karkkonen; S E Holm
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1992-12       Impact factor: 3.267

2.  Epidemiological and clinical aspects of invasive group A streptococcal infections and the streptococcal toxic shock syndrome.

Authors:  B K Eriksson; J Andersson; S E Holm; M Norgren
Journal:  Clin Infect Dis       Date:  1998-12       Impact factor: 9.079

3.  Identification of domains involved in superantigenicity of streptococcal pyrogenic exotoxin F (SpeF).

Authors:  A Eriksson; S E Holm; M Norgren
Journal:  Microb Pathog       Date:  1998-11       Impact factor: 3.738

4.  The crystal structure of staphylococcal enterotoxin type D reveals Zn2+-mediated homodimerization.

Authors:  M Sundström; L Abrahmsén; P Antonsson; K Mehindate; W Mourad; M Dohlsten
Journal:  EMBO J       Date:  1996-12-16       Impact factor: 11.598

5.  Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes.

Authors:  V Kapur; M W Majesky; L L Li; R A Black; J M Musser
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-15       Impact factor: 11.205

6.  Cloning, characterization and overexpression of a Streptococcus pyogenes gene encoding a new type of mitogenic factor.

Authors:  M Iwasaki; H Igarashi; Y Hinuma; T Yutsudo
Journal:  FEBS Lett       Date:  1993-09-27       Impact factor: 4.124

7.  Isolation, sequence and expression in Escherichia coli, Bacillus subtilis and Lactococcus lactis of the DNase (streptodornase)-encoding gene from Streptococcus equisimilis H46A.

Authors:  R Wolinowska; P Cegłowski; J Kok; G Venema
Journal:  Gene       Date:  1991-09-30       Impact factor: 3.688

8.  Crystal structure of the superantigen enterotoxin C2 from Staphylococcus aureus reveals a zinc-binding site.

Authors:  A C Papageorgiou; K R Acharya; R Shapiro; E F Passalacqua; R D Brehm; H S Tranter
Journal:  Structure       Date:  1995-08-15       Impact factor: 5.006

9.  Relation between low capacity of human sera to inhibit streptococcal mitogens and serious manifestation of disease.

Authors:  A Norrby-Teglund; K Pauksens; S E Holm; M Norgren
Journal:  J Infect Dis       Date:  1994-09       Impact factor: 5.226

10.  The superantigen streptococcal pyrogenic exotoxin C (SPE-C) exhibits a novel mode of action.

Authors:  P L Li; R E Tiedemann; S L Moffat; J D Fraser
Journal:  J Exp Med       Date:  1997-08-04       Impact factor: 14.307
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