| Literature DB >> 9873614 |
N Sakai1, C Ni, S M Bezrukov, S Matile.
Abstract
In this Letter, we describe the appearance of large, voltage-dependent currents in BLM induced by rigid rod-shaped polyols that function without charge and permanent dipole moment. The capacity of these symmetrical, nonpeptide models to form either short-living nanopores or small ion channels is shown to depend critically on the length of rigid-rod scaffold as well as the nature of the lateral side chains.Entities:
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Year: 1998 PMID: 9873614 DOI: 10.1016/s0960-894x(98)00481-8
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823