Literature DB >> 9873584

New antifungals selected by molecular topology.

L Pastor1, R García-Domenech, J Gálvez, S Wolski, M D García.   

Abstract

Molecular topology has been applied to find the new lead antimycotic compounds. Among the selected compounds stands out 3,3'-(4,4'-Biphenylene)bis(2,5-diphenyl-2H-tetrazolium chloride), Benztropine mesylate and Dicyclopentamethylenethiuram disulphide, with minimum inhibitory concentrations between 1.6 and 2 micrograms/mL.

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Year:  1998        PMID: 9873584     DOI: 10.1016/s0960-894x(98)00460-0

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  4 in total

1.  Optimization of a mathematical topological pattern for the prediction of antihistaminic activity.

Authors:  M J Duart; R García-Domenech; G M Antón-Fos; J Gálvez
Journal:  J Comput Aided Mol Des       Date:  2001-06       Impact factor: 3.686

2.  Indices of differences of path lengths: novel topological descriptors derived from electronic interferences in graphs.

Authors:  J Gálvez; R Garcia-Domenech; C de Gregorio-Alapont
Journal:  J Comput Aided Mol Des       Date:  2000-10       Impact factor: 3.686

3.  Silver coated bioactive glass particles for wound healing applications.

Authors:  A W Wren; A Coughlan; P Hassanzadeh; M R Towler
Journal:  J Mater Sci Mater Med       Date:  2012-03-17       Impact factor: 3.896

4.  Antifungal Activity of Salicylanilides and Their Esters with 4-(Trifluoromethyl)benzoic Acid.

Authors:  Martin Krátký; Jarmila Vinšová
Journal:  Molecules       Date:  2012-08-07       Impact factor: 4.411

  4 in total

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