Literature DB >> 9873547

A mixed resin bed for the quenching and purification of tetrabutylammonium fluoride mediated desilylating reactions.

J J Parlow1, M L Vazquez, D L Flynn.   

Abstract

A polymer-bound calcium sulfonate resin is prepared and used to sequester tetrabutylammonium fluoride. The simultaneous use of the calcium sulfonate resin with a sulfonic acid resin is used for the quenching and purification of desilylating reactions involving tetrabutylammonium fluoride as the reagent. Employment of this resin workup technique eliminates the need for a liquid-phase extractive protocol allowing the procedure to be easily automated.

Entities:  

Mesh:

Substances:

Year:  1998        PMID: 9873547     DOI: 10.1016/s0960-894x(98)00432-6

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  Operationally simple and efficient workup procedure for TBAF-mediated desilylation: application to halichondrin synthesis.

Authors:  Yosuke Kaburagi; Yoshito Kishi
Journal:  Org Lett       Date:  2007-02-15       Impact factor: 6.005

2.  2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase.

Authors:  Christopher J Matheson; Christopher R Coxon; Richard Bayliss; Kathy Boxall; Benoit Carbain; Andrew M Fry; Ian R Hardcastle; Suzannah J Harnor; Corine Mas-Droux; David R Newell; Mark W Richards; Mangaleswaran Sivaprakasam; David Turner; Roger J Griffin; Bernard T Golding; Céline Cano
Journal:  RSC Med Chem       Date:  2020-05-22
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.