Literature DB >> 9873478

Reaction of guanosine with glucose under oxidative conditions.

W Seidel1, M Pischetsrieder.   

Abstract

Incubation of glucose with guanosine under oxidative conditions at 37 degrees C or 70 degrees C leads to the formation of a main product, which can be detected by HPLC/DAD. The compound was isolated and identified as N2-carboxymethyl-guanosine (CMG). To confirm the structure, CMG was also synthesized from glyoxal and guanosine.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9873478     DOI： 10.1016/s0960-894x(98)00343-6

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

Review 1.  Molecular susceptibility to glycation and its implication in diabetes mellitus and related diseases.

Authors:  José D Méndez; Jianling Xie; Montserrat Aguilar-Hernández; Verna Méndez-Valenzuela
Journal:  Mol Cell Biochem       Date:  2010-07-31       Impact factor: 3.396

2.  Quantification of N2-carboxymethyl-2'-deoxyguanosine in calf thymus DNA and cultured human kidney epithelial cells by capillary high-performance liquid chromatography-tandem mass spectrometry coupled with stable isotope dilution method.

Authors:  Hongxia Wang; Huachuan Cao; Yinsheng Wang
Journal:  Chem Res Toxicol       Date:  2010-01       Impact factor: 3.739

3.  A hypothesis for examining dihydroxyacetone, the active component in sunless tanning products, as a topical prophylactic against SARS-COV-2 transmission.

Authors:  David M Perrin
Journal:  Med Hypotheses       Date:  2020-09-16       Impact factor: 1.538
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.