Literature DB >> 9873468

Novel angucycline compound with both antigastrin- and gastric mucosal protective-activities.

S Uesato1, T Tokunaga, K Takeuchi.   

Abstract

An angucycline series compound P371 A1 (1) from Streptomyces sp. P371 was established to have a novel structure comprising an ureido group at one of four sugar units on the basis of 2D NMR techniques. 1 exhibited an inhibitory activity against the pentagastrin-stimulated acid secretion as well as protective activities against HCl/ethanol- and indomethacin-induced gastric lesions.

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Year:  1998        PMID: 9873468     DOI: 10.1016/s0960-894x(98)00340-0

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

Review 1.  Astonishing diversity of natural surfactants: 5. Biologically active glycosides of aromatic metabolites.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2005-09       Impact factor: 1.880

Review 2.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

  2 in total

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