Literature DB >> 9873467

Peptidyl chemosensors incorporating a FRET mechanism for detection of Ni(II).

D A Pearce1, G K Walkup, B Imperiali.   

Abstract

Hexapeptides incorporating two fluorophores flanking a tripeptide sequence that binds Ni(II) and Cu(II) with high affinity have been synthesized. While Cu(II) quenches the fluorescence of the resulting peptides, coordination of Ni(II) enables enhanced FRET (fluorescent resonance energy transfer) from one fluorophore to the other.

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Year:  1998        PMID: 9873467     DOI: 10.1016/s0960-894x(98)00354-0

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  A turn-on fluorescent sensor for detecting nickel in living cells.

Authors:  Sheel C Dodani; Qiwen He; Christopher J Chang
Journal:  J Am Chem Soc       Date:  2009-12-23       Impact factor: 15.419

  1 in total

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