Literature DB >> 9873446

Serine derived NK1 antagonists. 2: A pharmacophore model for arylsulfonamide binding.

J M Elliott1, H Broughton, M A Cascieri, G Chicchi, I T Huscroft, M Kurtz, A M MacLeod, S Sadowski, G I Stevenson.   

Abstract

Modifications to the spirocyclic aryl sulfonamide portion of serine derived NK1 antagonists allow a partial pharmacophore model to be developed.

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Year:  1998        PMID: 9873446     DOI: 10.1016/s0960-894x(98)00319-9

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  A pharmacophore model for NK2 antagonist comprising compounds from several structurally diverse classes.

Authors:  Anders Poulsen; Tommy Liljefors; Klaus Gundertofte; Berith Bjørnholm
Journal:  J Comput Aided Mol Des       Date:  2002-04       Impact factor: 3.686

2.  Stereoselective syntheses of functionalized spirocyclopenteneoxindoles via triphenylphosphine-catalyzed [3+2] cycloaddition reactions.

Authors:  Qing-Fa Zhou; Xue-Ping Chu; Fei-Fei Ge; Cheng Li; Tao Lu
Journal:  Mol Divers       Date:  2013-06-19       Impact factor: 2.943

  2 in total

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