Literature DB >> 9873440

Modeling, synthesis and biological activity of novel antifungal agents (1).

T Tsukuda1, Y Shiratori, M Watanabe, H Ontsuka, K Hattori, M Shirai, N Shimma.   

Abstract

Homology modeling of candida lanosterol C-14 demethylase, synthesis and in vitro antifungal activities of cyclohexyl analogs of restricticin are described.

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Year:  1998        PMID： 9873440     DOI： 10.1016/s0960-894x(98)00316-3

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  10 in total

1.  Crystal structure of cytochrome P450 14alpha -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors.

Authors:  L M Podust; T L Poulos; M R Waterman
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-13       Impact factor: 11.205

2.  Synthesis and RP HPLC studies of biologically active semicarbazides and their cyclic analogues 1,2,4-triazol-3-ones.

Authors:  Monika Pitucha; Joanna Matysiak; Bogdan Senczyna
Journal:  Monatsh Chem       Date:  2012-01-28       Impact factor: 1.451

Review 3.  The Mechanistic Targets of Antifungal Agents: An Overview.

Authors:  Tryphon K Mazu; Barbara A Bricker; Hernan Flores-Rozas; Seth Y Ablordeppey
Journal:  Mini Rev Med Chem       Date:  2016       Impact factor: 3.862

4.  Three-dimensional models of wild-type and mutated forms of cytochrome P450 14alpha-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding.

Authors:  Li Xiao; Vincent Madison; Andrew S Chau; David Loebenberg; Robert E Palermo; Paul M McNicholas
Journal:  Antimicrob Agents Chemother       Date:  2004-02       Impact factor: 5.191

5.  2-Benzoylmethyl-4-[(2-benzylidene-ethylidene)amino]-5-(2-thienylmethyl)-2H-1,2,4-triazol-3(4H)-one.

Authors:  Reşat Ustabaş; Yasemin Unver; Nevin Suleymanoğlu; Ufuk Coruh; Kemal Sancak
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-04-08

6.  Ethyl 4-(3-ethyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-4-yl)benzoate.

Authors:  Yasemin Unver; Yavuz Köysal; Hasan Tanak; Dilek Unlüer; Samil Işık
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-05-08

7.  Ethyl 5-[6-(furan-2-yl)-1,2,4-triazolo[3,4-b][1,3,4]thia-diazol-3-yl]-2,6-di-methylnicotinate.

Authors:  Dongliang Lu; Min Zhang; Liping Song; Qiwen Tan; Min Shao
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2007-12-06

8.  Synthesis, antifungal and antibacterial activity of novel 1,2,4-triazole derivatives.

Authors:  Deepa Gupta; D K Jain
Journal:  J Adv Pharm Technol Res       Date:  2015 Jul-Sep

9.  Phenyl 1,2,3-triazole-thymidine ligands stabilize G-quadruplex DNA, inhibit DNA synthesis and potentially reduce tumor cell proliferation over 3'-azido deoxythymidine.

Authors:  Jerald Mahesh Kumar; Mohammed M Idris; Gunda Srinivas; Pallerla Vinay Kumar; Vuppalapaty Meghah; Mitta Kavitha; Chada Raji Reddy; Prathama S Mainkar; Biswajit Pal; Srivari Chandrasekar; Narayana Nagesh
Journal:  PLoS One       Date:  2013-08-19       Impact factor: 3.240

10.  Anti-Neuroinflammatory Agent, Restricticin B, from the Marine-Derived Fungus Penicillium janthinellum and Its Inhibitory Activity on the NO Production in BV-2 Microglia Cells.

Authors:  Byeoung-Kyu Choi; Song-Hee Jo; Dong-Kug Choi; Phan Thi Hoai Trinh; Hwa-Sun Lee; Van Anh Cao; Tran Thi Thanh Van; Hee Jae Shin
Journal:  Mar Drugs       Date:  2020-09-14       Impact factor: 5.118
  10 in total

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