| Literature DB >> 9872747 |
V R Iyer1, M B Eisen, D T Ross, G Schuler, T Moore, J C Lee, J M Trent, L M Staudt, J Hudson, M S Boguski, D Lashkari, D Shalon, D Botstein, P O Brown.
Abstract
The temporal program of gene expression during a model physiological response of human cells, the response of fibroblasts to serum, was explored with a complementary DNA microarray representing about 8600 different human genes. Genes could be clustered into groups on the basis of their temporal patterns of expression in this program. Many features of the transcriptional program appeared to be related to the physiology of wound repair, suggesting that fibroblasts play a larger and richer role in this complex multicellular response than had previously been appreciated.Entities:
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Year: 1999 PMID： 9872747 DOI： 10.1126/science.283.5398.83
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728